ChemicalBook > CAS DataBase List > N,N',N''-METHYLIDYNETRISFORMAMIDE

N,N',N''-METHYLIDYNETRISFORMAMIDE

Product Name
N,N',N''-METHYLIDYNETRISFORMAMIDE
CAS No.
4774-33-8
Chemical Name
N,N',N''-METHYLIDYNETRISFORMAMIDE
Synonyms
TRIS-FORMAMINOMETHANE;N-(diformamidomethyl)formamide;N-(diformamidomethyl)methanamide;N,N',N''-METHYLIDYNETRISFORMAMIDE;N,N',N''-Methanetriyltriformamide;Formamide, N,N',N''-methylidynetris-;N,N',N''-Methylidynetrisformamide 97%;Tris-formaminomethane/N,N',N''-Methylidynetrisformamide
CBNumber
CB5417058
Molecular Formula
C4H7N3O3
Formula Weight
145.12
MOL File
4774-33-8.mol
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N,N',N''-METHYLIDYNETRISFORMAMIDE Property

Melting point:
170-172 °C (dec.)(lit.)
Boiling point:
720.5±55.0 °C(Predicted)
Density 
1.280±0.06 g/cm3(Predicted)
solubility 
water: soluble25mg/mL, clear, colorless
pka
12.69±0.23(Predicted)
form 
solid
Water Solubility 
water: soluble 25mg/mL, clear, colorless
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
159735
Product name
N,N′,N′′-Methylidynetrisformamide
Purity
97%
Packaging
5g
Price
$100
Updated
2024/03/01
American Custom Chemicals Corporation
Product number
CHM0156734
Product name
N,N',N''-METHYLIDYNETRISFORMAMIDE
Purity
95.00%
Packaging
5G
Price
$857.66
Updated
2021/12/16
AHH
Product number
MT-20196
Product name
N,N',N''-Methylidynetrisformamide
Purity
98%
Packaging
1000g
Price
$538
Updated
2021/12/16
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N,N',N''-METHYLIDYNETRISFORMAMIDE Chemical Properties,Usage,Production

Uses

N,N′N′′-methylidynetrisformamide (TRIFO) is a source for formamide; used for N-formylformamidine (H2N-CH=N-CHO); for the N-formylformimidoyl group (H-C=NHCHO) as a building block in heterocyclic synthesis).

Preparation

Triethyl Orthoformate reacts with formamide under catalysis of mineral acids to give TRIFO (eq 1). The reaction of excess formamide with inorganic and organic acyl chlorides such as PCl3, POCl3, SOCl2, acetyl chloride, benzoyl chloride, and ethyl chloroformate proceeds via iminium salts to afford TRIFO. Analogously, alkylating reagents such as dialkyl sulfates, alkyl sulfonates or triethyloxonium tetrafluoroborate transform formamide to TRIFO. Alkoxymethyleneiminium salts and formamidinium salts are intermediates in these reactions. Pure salts of this type are also converted to the reagent by formamide. Reaction of Dimethyl Sulfate with formamide is the easiest way to prepare TRIFO.

General Description

N,N′,N′′-Methylidynetrisformamide is also referred as tris(formamido)methane.

Solubility in organics

N,N′N′′-methylidynetrisformamide is soluble in formamide; soluble in aprotic dipolar solvents such as DMF or DMA on heating.

storage

N,N′N′′-methylidynetrisformamide is stored at rt in closed bottles. Use in a fume hood.

N,N',N''-METHYLIDYNETRISFORMAMIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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N,N',N''-METHYLIDYNETRISFORMAMIDE Suppliers

Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44689
Advantage
61
Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Email
sales@capotchem.com
Country
China
ProdList
18207
Advantage
66
Beijing Ouhe Technology Co., Ltd
Tel
010-82967028 13552068683
Fax
+86-10-82967029
Email
2355560935@qq.com
Country
China
ProdList
12443
Advantage
60
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42958
Advantage
64
Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Country
China
ProdList
51456
Advantage
80
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131957
Advantage
58
Capot Chemical Co.,Ltd.
Tel
+86-(0)57185586718 +86-13336195806
Fax
+86-571-85864795
Email
sales@capot.com
Country
China
ProdList
29792
Advantage
60
Shaanxi Dideu Medichem Co. Ltd
Tel
+86-29-81139210 +86-18192627656
Fax
+86-29-88380327
Email
1059@dideu.com
Country
China
ProdList
3003
Advantage
58
Henan Kehong Biological Technology Co. LTD
Tel
0371-55969461; 0371-86658258 19139748274
Fax
QQ:3311217266
Email
info@kehobio.com
Country
China
ProdList
2555
Advantage
58
Bide Pharmatech Ltd.
Tel
400-1647117 13681763483
Email
product02@bidepharm.com
Country
China
ProdList
62075
Advantage
58
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View Lastest Price from N,N',N''-METHYLIDYNETRISFORMAMIDE manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
N,N',N''-METHYLIDYNETRISFORMAMIDE 4774-33-8
Price
US $1.00-22.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
100000KG
Release date
2024-07-16

4774-33-8, N,N',N''-METHYLIDYNETRISFORMAMIDERelated Search:


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  • N-(diformamidomethyl)formamide
  • N-(diformamidomethyl)methanamide
  • N,N',N''-Methylidynetrisformamide 97%
  • N,N',N''-METHYLIDYNETRISFORMAMIDE
  • Formamide, N,N',N''-methylidynetris-
  • N,N',N''-Methanetriyltriformamide
  • 4774-33-8
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