ChemicalBook > CAS DataBase List > Kv2-IN-A1
Kv2-IN-A1
- Product Name
- Kv2-IN-A1
- CAS No.
- 689297-68-5
- Chemical Name
- Kv2-IN-A1
- Synonyms
- Kv2-IN-A1;ry785，Kv2-IN-A1;KV2 channel inhibitor-1;Kv2-IN-A1, 10 mM in DMSO;Kv-2-IN-A1,Kv2 IN A1,Kv2INA1;3-(3-chlorophenyl)-N-[2-(1,3-thiazol-4-yl)-1H-1,3-benzodiazol-5-yl]butanamide;Benzenepropanamide, 3-chloro-β-methyl-N-[2-(4-thiazolyl)-1H-benzimidazol-6-yl]-
- CBNumber
- CB54199211
- Molecular Formula
- C20H17ClN4OS
- Formula Weight
- 396.89
- MOL File
- 689297-68-5.mol
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Kv2-IN-A1 Property
- form
- Solid
- color
- White to off-white
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N-Bromosuccinimide Price
AK Scientific
- Product number
- SYN5253
- Product name
- Kv2-IN-A1
- Packaging
- 100mg
- Price
- $2268
- Updated
- 2021/12/16
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Kv2-IN-A1 Chemical Properties,Usage,Production
Description
Kv2-IN-A1 is a Kv2.1 and Kv2.2 inhibitor.
Uses
KV2 channel inhibitor-1 is a selective KV2 channel inhibitor with IC50s of 0.2 μM and 0.41 μM for KV2.1 and KV2.2, respectively. KV2 channel inhibitor-1 possesses good selectivity over KV1.2 (IC50>10 μM). KV2 channel inhibitor-1 is >10-fold selective over NaV channels and other KV channels and displays weak activity on CaV channels[1].
References
[1] James Herrington, et al. Identification of novel and selective Kv2 channel inhibitors. Mol Pharmacol. 2011 Dec;80(6):959-64. DOI:10.1124/mol.111.074831
Kv2-IN-A1 Preparation Products And Raw materials
Raw materials
Preparation Products
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