ChemicalBook > CAS DataBase List > 1-OXAZOLO[4,5-B]PYRIDIN-2-YL-1-DODECANONE

1-OXAZOLO[4,5-B]PYRIDIN-2-YL-1-DODECANONE

Product Name
1-OXAZOLO[4,5-B]PYRIDIN-2-YL-1-DODECANONE
CAS No.
288862-73-7
Chemical Name
1-OXAZOLO[4,5-B]PYRIDIN-2-YL-1-DODECANONE
Synonyms
CAY10435;1-OXAZOLO[4,5-B]PYRIDIN-2-YL-1-DODECANONE;1-Dodecanone, 1-oxazolo[4,5-b]pyridin-2-yl-;1-([1,3]oxazolo[4,5-b]pyridin-2-yl)dodecan-1-one
CBNumber
CB5423194
Molecular Formula
C18H26N2O2
Formula Weight
302.41
MOL File
288862-73-7.mol
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1-OXAZOLO[4,5-B]PYRIDIN-2-YL-1-DODECANONE Property

Boiling point:
420.9±37.0 °C(Predicted)
Density 
1.044±0.06 g/cm3(Predicted)
solubility 
DMF: 10 mg/ml; DMSO: 10 mg/ml; DMSO:PBS (pH 7.2) (1:2): .05mg/ml; Ethanol: 10 mg/ml
pka
-1.77±0.50(Predicted)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
10005102
Product name
CAY10435
Purity
≥98%
Packaging
500μg
Price
$53
Updated
2023/06/20
Cayman Chemical
Product number
10005102
Product name
CAY10435
Purity
≥98%
Packaging
1mg
Price
$99
Updated
2023/06/20
Cayman Chemical
Product number
10005102
Product name
CAY10435
Purity
≥98%
Packaging
5mg
Price
$411
Updated
2023/06/20
Cayman Chemical
Product number
10005102
Product name
CAY10435
Purity
≥98%
Packaging
10mg
Price
$718
Updated
2023/06/20
AK Scientific
Product number
1312AH
Product name
1-Oxazolo[4,5-b]pyridin-2-yl-1-dodecanone
Packaging
5mg
Price
$564
Updated
2021/12/16
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1-OXAZOLO[4,5-B]PYRIDIN-2-YL-1-DODECANONE Chemical Properties,Usage,Production

Description

Fatty acid amide hydrolase (FAAH) is the enzyme responsible for hydrolysis and inactivation of fatty acid amides including anandamide and oleamide. CAY10435 is a selective, potent inhibitor of rat FAAH exhibiting a Ki value of 0.57 nM. Using a proteonomics approach, CAY10435 was screened against the serine hydrolase family of enzymes, of which FAAH is a member. In this assay, CAY10435 exhibited IC50 values of 0.81 nM, 83 nM, and 50 μM for FAAH, triacylglycerol hydrolase (TGH), and an uncharacterized hydrolase (KIAA1363), respectively. Knowledge of the specificity of CAY10435 obtained from this experiment should allow for more accurate interpretation of results using the inhibitor in complex environments such as whole cells or animals.

Definition

ChEBI: CAY10435 is an oxazolopyridine.

1-OXAZOLO[4,5-B]PYRIDIN-2-YL-1-DODECANONE Preparation Products And Raw materials

Raw materials

Preparation Products

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1-OXAZOLO[4,5-B]PYRIDIN-2-YL-1-DODECANONE Suppliers

China 15 Switzerland 1 United States 1 Global 17
Shanghai Hongye Biotechnology Co. Ltd
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288862-73-7, 1-OXAZOLO[4,5-B]PYRIDIN-2-YL-1-DODECANONERelated Search:

2-DODECANOYLOXAZOLE 2-NONANOYLOXAZOLE 2-UNDECANOYLOXAZOLE 2-OCTANOYLOXAZOLE 2-ETHYLOXAZOLO[4,5-B]PYRIDINE 2-DECANOYLOXAZOLE 2-HEPTANOYLOXAZOLE 1-OXAZOLO[4,5-B]PYRIDIN-2-YL-1-DODECANONE

  • CAY10435
  • 1-([1,3]oxazolo[4,5-b]pyridin-2-yl)dodecan-1-one
  • 1-OXAZOLO[4,5-B]PYRIDIN-2-YL-1-DODECANONE
  • 1-Dodecanone, 1-oxazolo[4,5-b]pyridin-2-yl-
  • 288862-73-7