ChemicalBook > CAS DataBase List > 3-BROMO-5-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)-PYRIDINE

3-BROMO-5-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)-PYRIDINE

Product Name
3-BROMO-5-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)-PYRIDINE
CAS No.
452972-13-3
Chemical Name
3-BROMO-5-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)-PYRIDINE
Synonyms
3-bromoyridine-5-borate acid;5-BROMO-3-PYRIDINEBORONIC ACID PINACOL &;3-BROMOPYRIDINE-5-BORONIC ACID PINACOL ESTER;5-BROMOPYRIDINE-3-BORONIC ACID, PINACOL ESTER;5-Bromo-3-pyridineboronic acid pinacol ester;3-bromo-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-y98%;3-bromo-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrid...;5-Bromo-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine;3-BROMO-5-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)-PYRIDINE;Pyridine, 3-bromo-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-
CBNumber
CB5423442
Molecular Formula
C11H15BBrNO2
Formula Weight
283.96
MOL File
452972-13-3.mol
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3-BROMO-5-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)-PYRIDINE Property

Melting point:
63.4-63.8°C
Boiling point:
341.4±27.0 °C(Predicted)
Density 
1.34
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
pka
2.86±0.22(Predicted)
Appearance
White to off-white Solid
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Safety

Hazard Codes 
Xi
Risk Statements 
36/38
Safety Statements 
26
WGK Germany 
3
HazardClass 
IRRITANT
HS Code 
2933399990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
674567
Product name
5-Bromo-3-pyridineboronic acid pinacol ester
Purity
90%
Packaging
1g
Price
$84
Updated
2023/06/20
TRC
Product number
B695658
Product name
5-Bromopyridine-3-boronicacid,pinacolester
Packaging
100mg
Price
$45
Updated
2021/12/16
TRC
Product number
B695658
Product name
5-Bromopyridine-3-boronicacid,pinacolester
Packaging
250mg
Price
$50
Updated
2021/12/16
TRC
Product number
B695658
Product name
5-Bromopyridine-3-boronicacid,pinacolester
Packaging
500mg
Price
$70
Updated
2021/12/16
Matrix Scientific
Product number
018242
Product name
3-Bromo-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-pyridine
Packaging
500mg
Price
$39
Updated
2021/12/16
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3-BROMO-5-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)-PYRIDINE Chemical Properties,Usage,Production

Synthesis

625-92-3

73183-34-3

452972-13-3

Preparation of compound 4-1 (5-bromopyridine-3-boronic acid pinacol ester) [221]: In a dry reaction flask 3,5-dibromopyridine (25 g, 105.5 mmol), pinacol ester of biboronic acid (28 g, 110.8 mmol), PdCl2(PPh3)2 (3.7 g, 5.27 mmol), and KOAc (20.7 g 211 mmol), and then 1,4-dioxane (211 mL) was added. The reaction mixture was stirred at reflux for 2 h at 120 °C. After completion of the reaction, it was cooled to room temperature and the organic layer was extracted with ethyl acetate. The organic layer was dried with anhydrous magnesium sulfate, filtered and concentrated. The crude product was purified by column chromatography to afford compound 4-1 (25 g, 86% yield) as a white solid.

References

[1] Patent: WO2016/186321, 2016, A1. Location in patent: Paragraph 220-221

3-BROMO-5-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)-PYRIDINE Preparation Products And Raw materials

Raw materials

Preparation Products

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3-BROMO-5-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)-PYRIDINE Suppliers

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View Lastest Price from 3-BROMO-5-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)-PYRIDINE manufacturers

Dideu Industries Group Limited
Product
3-BROMO-5-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)-PYRIDINE 452972-13-3
Price
US $1.10/g
Min. Order
1g
Purity
99.00%
Supply Ability
100 Tons min
Release date
2021-08-20
Shaanxi Dideu Medichem Co. Ltd
Product
5-Bromopyridine-3-boronic acid pinacol ester 452972-13-3
Price
US $0.00-0.00/Kg
Min. Order
1KG
Purity
99.0%
Supply Ability
500 MT
Release date
2020-05-12
Career Henan Chemical Co
Product
3-BROMO-5-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)-PYRIDINE 452972-13-3
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
1ton
Release date
2019-07-11

452972-13-3, 3-BROMO-5-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)-PYRIDINERelated Search:

3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine 5-Bromopyridine-3-boronic acid 2-BROMO-6-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PYRIDINE 2-BROMO-5-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PYRIDINE 2-BROMO-4-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)-PYRIDINE 3-BROMO-4-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)PYRIDINE 2-BROMO-3-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)-PYRIDINE 5-BROMO-2-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PYRIDINE 5-BROMO-2-METHOXY-3-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PYRIDINE 5-BROMO-2-FLUORO-3-(4,4,5,5-TETRAMETHYL-[1,3,2]-DIOXABOROLAN-2-YL)PYRIDINE 5-BROMO-2-TERT-BUTYLOXYCARBONYLAMINO PYRIDINE-3-BORONIC ACID PINACOL ESTER 5-BROMO-2-TERT-BUTYLOXYCARBONYLAMINO-6-METHYLPYRIDINE-3-BORONIC ACID PINACOL ESTER 5-BROMO-2-CHLORO-3-(4,4,5,5-TETRAMETHYL-[1,3,2]-DIOXABOROLAN-2-YL)PYRIDINE 3-BROMO-5-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)-PYRIDINE 2,5-DIBROMOPYRIDINE-3-BORONIC ACID PINACOL ESTER

  • 5-BROMO-3-PYRIDINEBORONIC ACID PINACOL &
  • 5-BROMOPYRIDINE-3-BORONIC ACID, PINACOL ESTER
  • 5-Bromo-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine
  • 5-Bromo-3-pyridineboronic acid pinacol ester
  • 3-bromo-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-y98%
  • 3-BROMO-5-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)-PYRIDINE
  • 3-BROMOPYRIDINE-5-BORONIC ACID PINACOL ESTER
  • Pyridine, 3-bromo-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-
  • 3-BROMO-5-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)-PYRIDINE ISO 9001：2015 REACH
  • 3-bromo-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrid...
  • 3-bromoyridine-5-borate acid
  • 452972-13-3
  • Heteroaryl
  • Organometallic Reagents
  • Boronate Esters
  • Boronic Acids and Derivatives