MAG-FURA-2, AM

MAG-FURA-2, AM Property

Melting point:

>200℃

Boiling point:

797.5±70.0 °C(Predicted)

Density 

1.436±0.06 g/cm3(Predicted)

storage temp. 

-20°C

solubility 

Insoluble in water; soluble in dimethyl sulfoxide, ethyl acetate

pka

-2.19±0.10(Predicted)

form 

powder

color 

Light yellow

Appearance

Solid Powder

λmax

366 nm

Biological Applications

Magnesium indicator; calcium indicator; zinc indicator

Hazard and Precautionary Statements (GHS)

MAG-FURA-2, AM Chemical Properties,Usage,Production

Description

Mag-fura-2 AM is a membrane-permeant, short-wavelength fluorescent indicator for intracellular magnesium. It can be loaded into cells via incubation, and hydrolyzed to mag-fura-2. Intracellular magnesium concentration can be measured by ratio of fluorescence intensity generated by mag-fura-2.

Uses

Calcium is an important part of the human body, usually in the form of calcium, a large number of bones and teeth of the human body, a small amount of blood and tissues. MCE calcium ion detection probe can specifically identify intracellular calcium ions, with high sensitivity, low cytotoxicity, increased AM acetylmethyl ester can enter the cell well, after being sheared by the intracellular esterase stay in the cell to bind to calcium ions, produce strong fluorescence, in addition, Mag-indo-1/AM and Mag-Fluo-4 AM at a certain concentration (usually 5 mM) can effectively identify intracellular magnesium ions[1].

storage

Store at -20°C

References

[1] García-Martín E, et, al. Intrasynaptosomal free Mg2+ concentration measured with the fluorescent indicator mag-fura-2: modulation by Na+ gradient and by extrasynaptosomal ATP. J Neurochem. 1995 Dec;65(6):2757-64. DOI:10.1046/j.1471-4159.1995.65062757.x

Excitation / Emission Maximum

537 nm/559 ±5 nm