4'-BROMOVALEROPHENONE
- Product Name
- 4'-BROMOVALEROPHENONE
- CAS No.
- 7295-44-5
- Chemical Name
- 4'-BROMOVALEROPHENONE
- Synonyms
- 4-BROMOVALEROPHENONE;P-BROMOVALEROPHENONE;4'-Bromovalerophenone;The broMobenzene ketone;4' -bromophenopentanone;Valerophenone, 4'-bromo-;p-Bromovalerophenone,98%;4'-Bromovalerophenone>1-Bromo-4-pentanoylbenzene;p-Bromophenyl butyl ketone
- CBNumber
- CB5454776
- Molecular Formula
- C11H13BrO
- Formula Weight
- 241.12
- MOL File
- 7295-44-5.mol
4'-BROMOVALEROPHENONE Property
- Melting point:
- 34-36 °C(lit.)
- Boiling point:
- 168-169 °C20 mm Hg(lit.)
- Density
- 1.3366 (rough estimate)
- refractive index
- 1.5290 (estimate)
- Flash point:
- >230 °F
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- Chloroform, Ethyl Acetate (Sparingly)
- form
- Solid
- color
- Tan
- λmax
- 325nm(Heptane)(lit.)
- InChI
- InChI=1S/C11H13BrO/c1-2-3-4-11(13)9-5-7-10(12)8-6-9/h5-8H,2-4H2,1H3
- InChIKey
- STYJKBMRWQQJIS-UHFFFAOYSA-N
- SMILES
- C(C1=CC=C(Br)C=C1)(=O)CCCC
- CAS DataBase Reference
- 7295-44-5(CAS DataBase Reference)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 221414
- Product name
- 4′-Bromovalerophenone
- Purity
- ≥98%
- Packaging
- 10g
- Price
- $97.5
- Updated
- 2023/01/07
- Product number
- B4733
- Product name
- 4'-Bromovalerophenone
- Purity
- >98.0%(GC)
- Packaging
- 5g
- Price
- $24
- Updated
- 2025/07/31
- Product number
- B4733
- Product name
- 4'-Bromovalerophenone
- Purity
- >98.0%(GC)
- Packaging
- 25g
- Price
- $77
- Updated
- 2025/07/31
- Product number
- B689025
- Product name
- 4''-Bromovalerophenone
- Packaging
- 25g
- Price
- $180
- Updated
- 2021/12/16
- Product number
- 337001
- Product name
- 1-(4-Bromophenyl)pentan-1-one
- Purity
- 95+%
- Packaging
- 100g
- Price
- $99
- Updated
- 2021/12/16
4'-BROMOVALEROPHENONE Chemical Properties,Usage,Production
Chemical Properties
yellow crystalline powder
Uses
4′-Bromovalerophenone may be used in chemical synthesis studies.
Uses
4'-Bromovalerophenone is a derivative of Valerophenone, which is an aromatic ketone that is often used as a tool in the study of various photochemical processes. Valerophenone is also an inhibitor of the enzyme carbonyl reductase.
Synthesis
693-03-8
18469-37-9
7295-44-5
GENERAL PROCEDURE: Trifluoromethanesulfonic anhydride (Tf2O, 1.2 eq.) was slowly added dropwise to a solution of 4-bromo-N,N-dimethylbenzamide (1.0 eq.) and 2,6-di-tert-butyl-4-methylpyridine (DTBMP, 1.2 eq.) in dichloromethane (CH2Cl2, 5 mL) cooled to -78 °C. The reaction mixture was gradually warmed up to 0 °C over 2 hours. Subsequently, a solution of butylmagnesium bromide (1.0 eq.) in ether (Et2O) was slowly added dropwise to the reaction mixture at -78 °C and stirring was continued at the same temperature for 2 hours. After completion of the reaction, the reaction was quenched with 15% aqueous hydrochloric acid (5 mL). The organic layer was separated and the aqueous phase was extracted with ether (3 x 5 mL). The organic layers were combined, washed with saturated saline, dried over anhydrous sodium sulfate (Na2SO4), filtered and concentrated under reduced pressure. The residue was purified by silica gel fast column chromatography to obtain the target product 4-bromovalerophenone. For the separation of the by-product N,N-dimethyl-4-bromobenzamide, the aqueous phase was alkalized with 15% aqueous sodium hydroxide (6 mL) and extracted with dichloromethane (3 x 10 mL). The organic layers were combined, dried over anhydrous sodium sulfate (Na2SO4), filtered and concentrated under reduced pressure. The residue was purified by silica gel fast column chromatography to give N,N-dimethyl-4-bromobenzamide.
References
[1] Tetrahedron, 2015, vol. 71, # 24, p. 4248 - 4254
4'-BROMOVALEROPHENONE Preparation Products And Raw materials
Raw materials
Preparation Products
4'-BROMOVALEROPHENONE Suppliers
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- Country
- Germany
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View Lastest Price from 4'-BROMOVALEROPHENONE manufacturers
- Product
- 4' -bromophenopentanone 7295-44-5
- Price
- US $15.00-9.00/kg
- Min. Order
- 1kg
- Purity
- 99.9%
- Supply Ability
- 50ton
- Release date
- 2024-06-12
- Product
- 4'-BROMOVALEROPHENONE 7295-44-5
- Price
- US $100.00/drum
- Min. Order
- 1drum
- Purity
- 99
- Supply Ability
- 5000
- Release date
- 2023-08-31
- Product
- 4'-BROMOVALEROPHENONE 7295-44-5
- Price
- US $1.00/g
- Min. Order
- 1g
- Purity
- 99%min
- Supply Ability
- 100kg
- Release date
- 2020-03-06