NOCICEPTIN (1-7)
- Product Name
- NOCICEPTIN (1-7)
- CAS No.
- 178249-42-8
- Chemical Name
- NOCICEPTIN (1-7)
- Synonyms
- NOCICEPTIN (1-7);Nociceptin Fragment 1-7;Orphanin FQ Fragment 1-7;Nociceptin (1-7)、1-7-Orphanin FQ (pig);Nociceptin (1-7) (Orphanin FQ (1-7)), Endogenous ligand for ORL1;L-Alanine, L-phenylalanylglycylglycyl-L-phenylalanyl-L-threonylglycyl-
- CBNumber
- CB5458365
- Molecular Formula
- C31H41N7O9
- Formula Weight
- 655.7
- MOL File
- Mol file
NOCICEPTIN (1-7) Property
- Boiling point:
- 1193.6±65.0 °C(Predicted)
- Density
- 1.319±0.06 g/cm3(Predicted)
- storage temp.
- −20°C
- form
- Powder
- pka
- 3.42±0.10(Predicted)
- Water Solubility
- Soluble to 2 mg/ml in water
- Sequence
- Phe-Gly-Gly-Phe-Thr-Gly-Ala
Safety
- WGK Germany
- 3
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- N634103
- Product name
- Nociceptin(1-7)
- Packaging
- 1mg
- Price
- $215
- Updated
- 2021/12/16
- Product number
- B5087
- Product name
- Nociceptin(1-7)
- Packaging
- 1mg
- Price
- $339
- Updated
- 2021/12/16
- Product number
- PEP0003912
- Product name
- NOCICEPTIN (1-7)
- Purity
- 95.00%
- Packaging
- 1MG
- Price
- $733.72
- Updated
- 2021/12/16
NOCICEPTIN (1-7) Chemical Properties,Usage,Production
Uses
Nociceptin (1-7), also known as orphanin FQ, is identified as naturally occurring agonist of orphan opioid receptor-like ORL1 receptor.
in vivo
Nociceptin (1-7) (intrathecal injection; 150–1200 nmol; single dose) has no significant effect in the nociceptive thermal threshold (hyperalgesia). However, when nociceptin (1–7) is injected simultaneously with nociceptin (3.0fmol), nociceptin-induced hyperalgesia is significantly reduced[1].
| Animal Model: | Mice[1] |
| Dosage: | 150–1200 nmol |
| Administration: | Intrathecal injection; single dose |
| Result: | Co-treatment with nociceptin could reduce hyperalgesia. |
IC 50
NOP Receptor/ORL1
NOCICEPTIN (1-7) Preparation Products And Raw materials
Raw materials
Preparation Products
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