ChemicalBook > CAS DataBase List > LOSARTAN-D4

LOSARTAN-D4

Product Name
LOSARTAN-D4
CAS No.
1030937-27-9
Chemical Name
LOSARTAN-D4
Synonyms
MK-954-d4;Cozaar-d4;DuP-753 D4;LOSARTAN-D4;D4-Losartan;[2H4]-Losartan;Reaxys ID: 18951469;Losartan-d4 in methanol;2-Butyl-4-chloro-1-[[2'-(1H-tetrazol-5yl)[1,1'-biphenyl-d4]-4-yl]Methyl]-1H-iMidazole-5-Methanol;(1-((2'-(1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl-2,3,5,6-d4)methyl)-2-butyl-4-chloro-1H-imidazol-5-yl
CBNumber
CB5465064
Molecular Formula
C22H19ClD4N6O
Formula Weight
426.94
MOL File
Mol file
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LOSARTAN-D4 Property

Melting point:
184-190?C
storage temp. 
-20°C Freezer, Under Inert Atmosphere
solubility 
Chloroform (Slightly),Ethyl Acetate (Slightly), Methanol (Slightly)
form 
Solid
color 
White to Off-White
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
22567
Product name
Losartan-d4
Purity
≥99% deuterated forms (d1-d4)
Packaging
500μg
Price
$121
Updated
2024/03/01
Cayman Chemical
Product number
22567
Product name
Losartan-d4
Purity
≥99% deuterated forms (d1-d4)
Packaging
1mg
Price
$230
Updated
2024/03/01
TRC
Product number
L470503
Product name
Losartan-d4
Packaging
25mg
Price
$2025
Updated
2021/12/16
Usbiological
Product number
015677
Product name
Losartan-d4
Packaging
1mg
Price
$460
Updated
2021/12/16
Apolloscientific
Product number
BICR171
Product name
Losartan-D4
Packaging
5mg
Price
$493
Updated
2021/12/16
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LOSARTAN-D4 Chemical Properties,Usage,Production

Description

Losartan-D4 is a deuterium-labeled version of Losartan, which is an angiotensin II receptor antagonist that competes with the binding of angiotensin II to AT1 receptors with an IC50 of 20 nM. Losartan is an antagonist of the angiotensin (AT) II receptor subtype AT1 with a K i value of 5-20 nM. 

Chemical Properties

White Solid

Uses

A labelled version of Losartan, a nonpeptide angiotensin II AT1-receptor antagonist. Antihypertensive.

Uses

As a labelled version of Losartan, Losartan-d4 can be used as a nonpeptide angiotensin II AT1-receptor antagonist and Antihypertensive.

Uses

Losartan-d4 can be intended for use as an internal standard for the quantification of Losartan by GC- or LC-mass spectrometry.

IC 50

AT1 Receptor

LOSARTAN-D4 Preparation Products And Raw materials

Raw materials

Preparation Products

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1030937-27-9, LOSARTAN-D4Related Search:


  • Reaxys ID: 18951469
  • 2-Butyl-4-chloro-1-[[2'-(1H-tetrazol-5yl)[1,1'-biphenyl-d4]-4-yl]Methyl]-1H-iMidazole-5-Methanol
  • Cozaar-d4
  • MK-954-d4
  • LOSARTAN-D4
  • 2-Butyl-4-chloro-1-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl-2,3,5,6-d<sub>4</sub>]methyl]-1H-imidazole-5-methanol
  • [2H4]-Losartan
  • DuP-753 D4
  • Losartan D4Q: What is Losartan D4 Q: What is the CAS Number of Losartan D4 Q: What is the storage condition of Losartan D4 Q: What are the applications of Losartan D4
  • (1-((2'-(2H-Tetrazol-5-yl)-[1,1'-biphenyl]-4-yl-2,3,5,6-d4)methyl)-2-butyl-4-chloro-1H-imidazol-5-yl)methanol
  • (2-butyl-4-chloro-1-{[2'-(1H-1,2,3,4-tetrazol-5-yl)(2,3,5,6-2H?)-[1,1'-biphenyl]-4-yl]methyl}-1H-imidazol-5-yl)methanol
  • Losartan-d4 in methanol
  • (1-((2'-(1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl-2,3,5,6-d4)methyl)-2-butyl-4-chloro-1H-imidazol-5-yl
  • (1-((2'-(2H-Tetrazol-5-yl)-[1,1'-biphenyl]-4-yl-2,3,5,6-d4)methyl)-2-butyl-4-chloro-1H-imidazol-5-yl)methanol
  • D4-Losartan
  • 1030937-27-9
  • C22H19ClD4N6O
  • C22H19D4ClN6O
  • Heterocycles
  • Intermediates & Fine Chemicals
  • Isotope Labelled Compounds
  • Pharmaceuticals