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Biotin-sar-oh

Product Name
Biotin-sar-oh
CAS No.
154024-76-7
Chemical Name
Biotin-sar-oh
Synonyms
Biotin-sar-oh;CAS_154024-76-7;Biotin Impurity 68;N-Biotinyl-sarcosine;(+)-Biotin-sarcosine;2-[N-Methyl-5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanamido]acetic Acid;Glycine,N-[5-(hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl)-1-oxopentyl]-N-methyl-, [3aS-(3aa,4b,6aa)]-;2-[5-[(3aS,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]pentanoyl-methylamino]acetic acid;Glycine, N-[5-(hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl)-1-oxopentyl]-N-methyl-, [3aS-(3aα,4β,6aα)]- (9CI)
CBNumber
CB54660885
Molecular Formula
C13H21N3O4S
Formula Weight
315.39
MOL File
154024-76-7.mol
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Biotin-sar-oh Property

Boiling point:
646.1±50.0 °C(Predicted)
Density 
1.278±0.06 g/cm3(Predicted)
pka
3.61±0.10(Predicted)
form 
solid
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

AK Scientific
Product number
4176AH
Product name
(+)-Biotin-sarcosine
Packaging
250mg
Price
$137
Updated
2021/12/16
AK Scientific
Product number
4176AH
Product name
(+)-Biotin-sarcosine
Packaging
1g
Price
$244
Updated
2021/12/16
AK Scientific
Product number
4176AH
Product name
(+)-Biotin-sarcosine
Packaging
5g
Price
$824
Updated
2021/12/16
AK Scientific
Product number
4176AH
Product name
(+)-Biotin-sarcosine
Packaging
10g
Price
$1357
Updated
2021/12/16
AK Scientific
Product number
4176AH
Product name
(+)-Biotin-sarcosine
Packaging
25g
Price
$2451
Updated
2021/12/16
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Biotin-sar-oh Chemical Properties,Usage,Production

Uses

Biotin-sar-oh is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

Biological Activity

Biotin-sar-oh is a cleavable ADC linker that can be used to synthesize antibody-drug conjugates (ADCs).

in vitro

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

target

Cleavable

IC 50

Cleavable Linker

References

[1] Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337. DOI:10.1038/nrd.2016.268

Biotin-sar-oh Preparation Products And Raw materials

Raw materials

Preparation Products

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Biotin-sar-oh Suppliers

Borenpharm Co., Ltd
Tel
027-65563561
Fax
86-27-59218822
Email
sales@borenpharm.com
Country
China
ProdList
1245
Advantage
55
Wuxi Asia Peptide Biotechnology Limited Company
Tel
0510-83583050 13771062561
Fax
0510-83583039
Email
willsun@peptide-search.com
Country
China
ProdList
6716
Advantage
58
Beijing Jin Ming Biotechnology Co., Ltd.
Tel
010-60605840 18892239720
Fax
010-60605840
Email
psaitong@jm-bio.com
Country
China
ProdList
12306
Advantage
58
Amatek Scientific Co. Ltd.
Tel
0512-56316828
Fax
0512-56316826
Email
info@amateksci.com
Country
China
ProdList
28785
Advantage
58
SHANGHAI FDC-CHEMICAL CO.,LTD
Tel
021-61469567 13482353728
Fax
021-61161605
Email
sales@fdc-chemical.com
Country
China
ProdList
9717
Advantage
58
Kanghua (Shanghai) New Drug Development Co., Ltd.
Tel
021-61263370 18901917034
Email
xingli@glbiochem.com
Country
China
ProdList
5637
Advantage
58
Shanghai Jifeng Biotechnology Co., Ltd.
Tel
021-61263377 15023907684
Fax
021-61263399
Email
15800684150@163.com
Country
China
ProdList
8131
Advantage
58
BOC Sciences
Tel
16314854226; +16314854226
Email
inquiry@bocsci.com
Country
United States
ProdList
19654
Advantage
58
GL Biochem (Shanghai) Ltd.
Tel
+86-021-61263370 +86-18901917034
Country
CHINA
ProdList
3904
Advantage
58
GL Biochem(Binhai) Ltd.
Tel
+86-021-61263370 +8615301650015
Email
wuqiuyan@glschina.com
Country
China
ProdList
2975
Advantage
58

154024-76-7, Biotin-sar-ohRelated Search:


  • Biotin-sar-oh
  • CAS_154024-76-7
  • 2-[5-[(3aS,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]pentanoyl-methylamino]acetic acid
  • Glycine,N-[5-(hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl)-1-oxopentyl]-N-methyl-, [3aS-(3aa,4b,6aa)]-
  • Glycine, N-[5-(hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl)-1-oxopentyl]-N-methyl-, [3aS-(3aα,4β,6aα)]- (9CI)
  • Biotin Impurity 68
  • (+)-Biotin-sarcosine
  • N-Biotinyl-sarcosine
  • 2-[N-Methyl-5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanamido]acetic Acid
  • 154024-76-7