ChemicalBook > CAS DataBase List > (11,12-DiHETE

(11,12-DiHETE

Product Name
(11,12-DiHETE
CAS No.
867350-92-3
Chemical Name
(11,12-DiHETE
Synonyms
(11,12-DiHETE;11,12-dihydroxy-5(Z),8(Z),14(Z),17(Z)-Eicosapentaenoic acid;11,12-dihydroxy-5(Z),8(Z),14(Z),17(Z)-eicosatetraenoic acid;5,8,14,17-Eicosatetraenoic acid, 11,12-dihydroxy-, (5Z,8Z,14Z,17Z)-
CBNumber
CB54665668
Molecular Formula
C20H32O4
Formula Weight
336.47
MOL File
867350-92-3.mol
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(11,12-DiHETE Property

Boiling point:
515.8±50.0 °C(Predicted)
Density 
1.040±0.06 g/cm3(Predicted)
solubility 
DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 30 mg/ml; PBS (pH 7.2): 0.5 mg/ml
pka
4.75±0.10(Predicted)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H225Highly Flammable liquid and vapour

H350May cause cancer

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P233Keep container tightly closed.

P240Ground/bond container and receiving equipment.

P241Use explosion-proof electrical/ventilating/lighting/…/equipment.

P242Use only non-sparking tools.

P243Take precautionary measures against static discharge.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P308+P313IF exposed or concerned: Get medical advice/attention.

P370+P378In case of fire: Use … for extinction.

P403+P235Store in a well-ventilated place. Keep cool.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical
Product number
10466
Product name
(±)11,12-DiHETE
Purity
≥98%
Packaging
25μg
Price
$105
Updated
2024/03/01
Cayman Chemical
Product number
10466
Product name
(±)11,12-DiHETE
Purity
≥98%
Packaging
50μg
Price
$195
Updated
2024/03/01
Cayman Chemical
Product number
10466
Product name
(±)11,12-DiHETE
Purity
≥98%
Packaging
100μg
Price
$369
Updated
2024/03/01
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(11,12-DiHETE Chemical Properties,Usage,Production

Description

(±)11(12)-DiHETE is a dihydroxy metabolite of EPA produced by cytochrome P450-mediated epoxide formation and subsequent hydrolysis by epoxide hydrolase. Plasma levels of (±)11(12)-DiHETE are increased over baseline after an oral dose of 1008 mg EPA.1

Definition

ChEBI: 11,12-DiHETE is a polyunsaturated fatty acid and a hydroxy fatty acid.

References

1. Schuchardt, J.P., Schneider, I., Willenberg, I., et al. Increase of EPA-derived hydroxy, epoxy and dihydroxy fatty acid levels in human plasma after a single dose of long-chain omega-3 PUFA Prostaglandins Other Lipid Mediat. 109-111,23-31(2014).

(11,12-DiHETE Preparation Products And Raw materials

Raw materials

Preparation Products

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(11,12-DiHETE Suppliers

Alfa Chemistry
Tel
1-516-6625404
Fax
1-516-927-0118
Email
support@alfa-chemistry.com
Country
United States
ProdList
9171
Advantage
60
TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
32161
Advantage
58
Alfa Chemistry
Tel
Fax
1-516-927-0118
Email
Info@alfa-chemistry.com
Country
United States
ProdList
24072
Advantage
58
Cayman Chemical Company
Tel
--
Fax
--
Email
cayman@caymanchem.com
Country
United States
ProdList
6213
Advantage
81

867350-92-3, (11,12-DiHETERelated Search:


  • (11,12-DiHETE
  • 11,12-dihydroxy-5(Z),8(Z),14(Z),17(Z)-eicosatetraenoic acid
  • 11,12-dihydroxy-5(Z),8(Z),14(Z),17(Z)-Eicosapentaenoic acid
  • 5,8,14,17-Eicosatetraenoic acid, 11,12-dihydroxy-, (5Z,8Z,14Z,17Z)-
  • 867350-92-3