ChemicalBook > CAS DataBase List > PF-06860932

PF-06860932

Product Name
PF-06860932
CAS No.
2226970-01-8
Chemical Name
PF-06860932
Synonyms
PF-06860932;CFTR corrector 6;7H-Pyrrolo[2,3-d]pyrimidine-6-carbonitrile, 4-amino-7-[[1-(2-fluorophenyl)-1H-pyrazol-4-yl]methyl]-5-[2-(trifluoromethyl)-5-pyrimidinyl]-
CBNumber
CB54667293
Molecular Formula
C22H13F4N9
Formula Weight
479.39
MOL File
2226970-01-8.mol
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PF-06860932 Property

Boiling point:
697.4±55.0 °C(Predicted)
Density 
1.60±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
pka
3.23±0.30(Predicted)
form 
Solid
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene
Product number
CS-0135420
Product name
CFTRcorrector6
Packaging
5mg
Price
$480
Updated
2021/12/16
ChemScene
Product number
CS-0135420
Product name
CFTRcorrector6
Packaging
10mg
Price
$800
Updated
2021/12/16
ChemScene
Product number
CS-0135420
Product name
CFTRcorrector6
Packaging
25mg
Price
$1550
Updated
2021/12/16
ChemScene
Product number
CS-0135420
Product name
CFTRcorrector6
Packaging
50mg
Price
$2400
Updated
2021/12/16
ChemScene
Product number
CS-0135420
Product name
CFTRcorrector6
Packaging
100mg
Price
$3600
Updated
2021/12/16
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PF-06860932 Chemical Properties,Usage,Production

Biological Activity

CFTR corrector 6 is a potent potentiator of Cystic Fibrosis Transmembrane conductance Regulator (CFTR). CFTR corrector 6 has the potential for cystic fibrosis (CF) and other CFTR associated disorders research[1]. CFTR corrector 6 (Example 27) has EC50s of 1.25 nM and 1.27 nM for primary cystic fibrosis human bronchial epithelial (CF hBE) cells and fischer rat thyroid (FRT) cell lines[1].

References

[1]. Joseph Walter Strohbach, et al. Pyrrolopyrimidines as cftr potentiators. WO2018094137A1

PF-06860932 Preparation Products And Raw materials

Raw materials

Preparation Products

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PF-06860932 Suppliers

Kaixin Chemical (Hong Kong) Limited
Tel
010-88886666-01 13112345678
Fax
CDXH21@126.com
Email
loyson@tcypharm.com
Country
China
ProdList
595
Advantage
55
NINGBOBENKANGJS PHARMTECHCO., LTD
Tel
+8615990591583 15990591583
Country
CHINA
ProdList
2029
Advantage
58
Ningbo Benkang jishi Pharmaceutical Technology Co., Ltd.
Tel
15990591583
Fax
qq: 1050376806 mailbox : sales@nbpharmabridge.com
Country
China
ProdList
5573
Advantage
58
TargetMol Chemicals Inc.
Tel
4008200310
Email
marketing@tsbiochem.com
Country
China
ProdList
24647
Advantage
58
Shanghai Yifei Biotechnology Co. , Ltd.
Tel
021-65675885 18964387627
Email
customer_service@efebio.com
Country
China
ProdList
11974
Advantage
58
Shanghai?Medlife?Pharm-Tech?Co.,?Ltd
Tel
021-59167510 18117107507
Email
vip@med-life.cn
Country
China
ProdList
4997
Advantage
58
RD International Technology Co., Limited
Tel
18024082417
Email
market@ubiochem.com
Country
China
ProdList
9272
Advantage
58

2226970-01-8, PF-06860932Related Search:


  • PF-06860932
  • CFTR corrector 6
  • 7H-Pyrrolo[2,3-d]pyrimidine-6-carbonitrile, 4-amino-7-[[1-(2-fluorophenyl)-1H-pyrazol-4-yl]methyl]-5-[2-(trifluoromethyl)-5-pyrimidinyl]-
  • 2226970-01-8