ChemicalBook > CAS DataBase List > PF-06860932
PF-06860932
- Product Name
- PF-06860932
- CAS No.
- 2226970-01-8
- Chemical Name
- PF-06860932
- Synonyms
- PF-06860932;CFTR corrector 6;7H-Pyrrolo[2,3-d]pyrimidine-6-carbonitrile, 4-amino-7-[[1-(2-fluorophenyl)-1H-pyrazol-4-yl]methyl]-5-[2-(trifluoromethyl)-5-pyrimidinyl]-
- CBNumber
- CB54667293
- Molecular Formula
- C22H13F4N9
- Formula Weight
- 479.39
- MOL File
- 2226970-01-8.mol
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PF-06860932 Property
- Boiling point:
- 697.4±55.0 °C(Predicted)
- Density
- 1.60±0.1 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- pka
- 3.23±0.30(Predicted)
- form
- Solid
- color
- White to off-white
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N-Bromosuccinimide Price
ChemScene
- Product number
- CS-0135420
- Product name
- CFTRcorrector6
- Packaging
- 5mg
- Price
- $480
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-0135420
- Product name
- CFTRcorrector6
- Packaging
- 10mg
- Price
- $800
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-0135420
- Product name
- CFTRcorrector6
- Packaging
- 25mg
- Price
- $1550
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-0135420
- Product name
- CFTRcorrector6
- Packaging
- 50mg
- Price
- $2400
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-0135420
- Product name
- CFTRcorrector6
- Packaging
- 100mg
- Price
- $3600
- Updated
- 2021/12/16
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PF-06860932 Chemical Properties,Usage,Production
Biological Activity
CFTR corrector 6 is a potent potentiator of Cystic Fibrosis Transmembrane conductance Regulator (CFTR). CFTR corrector 6 has the potential for cystic fibrosis (CF) and other CFTR associated disorders research[1]. CFTR corrector 6 (Example 27) has EC50s of 1.25 nM and 1.27 nM for primary cystic fibrosis human bronchial epithelial (CF hBE) cells and fischer rat thyroid (FRT) cell lines[1].
References
[1]. Joseph Walter Strohbach, et al. Pyrrolopyrimidines as cftr potentiators. WO2018094137A1
PF-06860932 Preparation Products And Raw materials
Raw materials
Preparation Products
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PF-06860932 Suppliers
- Tel
- 010-88886666-01 13112345678
- Fax
- CDXH21@126.com
- loyson@tcypharm.com
- Country
- China
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- Tel
- +8615990591583 15990591583
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- CHINA
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- Tel
- 15990591583
- Fax
- qq: 1050376806 mailbox : sales@nbpharmabridge.com
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- China
- ProdList
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- Advantage
- 58
- Tel
- 4008200310
- marketing@tsbiochem.com
- Country
- China
- ProdList
- 24647
- Advantage
- 58
- Tel
- 021-65675885 18964387627
- customer_service@efebio.com
- Country
- China
- ProdList
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- Advantage
- 58
- Tel
- 021-59167510 18117107507
- vip@med-life.cn
- Country
- China
- ProdList
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- Tel
- 18024082417
- market@ubiochem.com
- Country
- China
- ProdList
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- Advantage
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