enalapril sodium salt

Product Name: enalapril sodium salt
CAS No.: 149404-21-7
Chemical Name: enalapril sodium salt
Synonyms: Enalapril sodium;(-)-Enalapril sodium;enalapril sodium salt
CBNumber: CB54667435
Molecular Formula: C20H29N2NaO5
Formula Weight: 400.45
MOL File: 149404-21-7.mol

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enalapril sodium salt Chemical Properties,Usage,Production

Uses

Enalapril (MK-421) sodium is an angiotensin-converting enzyme (ACE) inhibitor, can be used for hypertensive diseases research[1][2].

in vivo

Enalapril sodium (intraperitoneal injection, 0.03 mg/kg, once) reduces infarct volume due to middle cerebral artery occlusion and lower or higher doses are ineffective in Male NMRI mice^[4].

Animal Model:	Male NMRI mice 20-40 g^[4]
Dosage:	0.03 mg/kg
Administration:	Intraperitoneal injection; once
Result:	Reduced the area of middle cerebral artery infarction in mice at 0.03 mg/kg.

References

[1] Serge Sicouri, et al. Antiarrhythmic effects of losartan and enalapril in canine pulmonary vein sleeve preparations. J Cardiovasc Electrophysiol. 2011 Jun;22(6):698-705. DOI:10.1111/j.1540-8167.2010.01972.x
[2] Rokhsareh Meamar, et al. Enalapril protects endothelial cells against induced apoptosis in Alzheimer's disease. J Res Med Sci. 2013 Mar;18(Suppl 1):S1-5. PMID:23961275
[3] Talita A Cunha, et al. Effect of stearic acid on enalapril stability and dissolution from multiparticulate solid dosage forms. AAPS PharmSciTech. 2013 Sep;14(3):1150-7. DOI:10.1208/s12249-013-0006-6
[4] A Ravati, et al. Enalapril and moexipril protect from free radical-induced neuronal damage in vitro and reduce ischemic brain injury in mice and rats. Eur J Pharmacol. 1999 May 28;373(1):21-33. DOI:10.1016/s0014-2999(99)00211-3

enalapril sodium salt Preparation Products And Raw materials

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enalapril sodium salt Suppliers

China 3 United States 2 Global 5

Guangzhou Isun Pharmaceutical Co., Ltd

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TargetMol Chemicals Inc.

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TargetMol Chemicals Inc.

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TargetMol Chemicals Inc.

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149404-21-7, enalapril sodium saltRelated Search:

Enalapril sodium

enalapril sodium salt

(-)-Enalapril sodium

149404-21-7