GSK-656
- Product Name
- GSK-656
- CAS No.
- 2131798-13-3
- Chemical Name
- GSK-656
- Synonyms
- GSK-070;GSK-656;GSK656 HCl;GSK-3036656;GSK656,GSK-656;Ganfeborole HCl;GSK656 hydrochloride;Ganfeborole hydrochloride;GSK3036656 HCl|||GSK656 HCl;GSK656 HCl (GSK3036656, GSK070)
- CBNumber
- CB54667990
- Molecular Formula
- C10H14BCl2NO4
- Formula Weight
- 293.94
- MOL File
- 2131798-13-3.mol
GSK-656 Property
- storage temp.
- Store at -20°C
- solubility
- DMSO:67.5(Max Conc. mg/mL);229.64(Max Conc. mM)
- form
- Solid
- color
- Off-white to light yellow
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H301Toxic if swalloed
H373May cause damage to organs through prolonged or repeated exposure
- Precautionary statements
-
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P314Get medical advice/attention if you feel unwell.
P321Specific treatment (see … on this label).
P330Rinse mouth.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- CS-0030140
- Product name
- GSK656
- Purity
- 99.66%
- Packaging
- 5mg
- Price
- $550
- Updated
- 2021/12/16
- Product number
- BG168490
- Product name
- GSK 656
- Packaging
- 10mg
- Price
- $600
- Updated
- 2021/12/16
- Product number
- CS-0030140
- Product name
- GSK656
- Purity
- 99.66%
- Packaging
- 10mg
- Price
- $850
- Updated
- 2021/12/16
- Product number
- CS-0030140
- Product name
- GSK656
- Purity
- 99.66%
- Packaging
- 25mg
- Price
- $1700
- Updated
- 2021/12/16
- Product number
- BG168490
- Product name
- GSK 656
- Packaging
- 50mg
- Price
- $1850
- Updated
- 2021/12/16
GSK-656 Chemical Properties,Usage,Production
Uses
Ganfeborole hydrochloride (GSK656) is a potent antitubercular agent, acting as an inhibitor of Mycobacterium tuberculosis (Mtb) leucyl-tRNA synthetase (LeuRS), with an IC50 of 0.2 μM.
in vivo
Ganfeborole hydrochloride shows potent antitubercular activity in mice infected with M. tuberculosis H37Rv, with ED99 of 0.4 mg/kg[1].
References
[1] Li X, et al. Discovery of a Potent and Specific M. tuberculosis Leucyl-tRNA Synthetase Inhibitor: (S)-3-(Aminomethyl)-4-chloro-7-(2-hydroxyethoxy)benzo[c][1,2]oxaborol-1(3H)-ol (GSK656). J Med Chem. 2017 Oct 12;60(19):8011-8026. DOI:10.1021/acs.jmedchem.7b00631
GSK-656 Preparation Products And Raw materials
Raw materials
Preparation Products
GSK-656 Suppliers
- Tel
- +1-781-999-5354; +17819995354
- marketing@targetmol.com
- Country
- United States
- ProdList
- 32435
- Advantage
- 58
- Tel
- +1-708-310-1919 +1-13798911105
- Fax
- 708-557-7486
- sales@invivochem.cn
- Country
- United States
- ProdList
- 6391
- Advantage
- 58
- Tel
- +1-781-999-5354;
- support@targetmol.com
- Country
- United States
- ProdList
- 39035
- Advantage
- 58
View Lastest Price from GSK-656 manufacturers
- Product
- GSK-656 2131798-13-3
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-06-26