Praliciguat
- Product Name
- Praliciguat
- CAS No.
- 1628730-49-3
- Chemical Name
- Praliciguat
- Synonyms
- IW-1973;Praliciguat;Praliciguat, 10 mM in DMSO;Praliciguat,IW 1973,Guanylate Cyclase,Inhibitor,IW1973,inhibit;2-Propanol, 1,1,1,3,3,3-hexafluoro-2-[[[5-fluoro-2-[1-[(2-fluorophenyl)methyl]-5-(3-isoxazolyl)-1H-pyrazol-3-yl]-4-pyrimidinyl]amino]methyl]-
- CBNumber
- CB54668407
- Molecular Formula
- C21H14F8N6O2
- Formula Weight
- 534.36
- MOL File
- 1628730-49-3.mol
Praliciguat Property
- Boiling point:
- 588.5±50.0 °C(Predicted)
- Density
- 1.60±0.1 g/cm3(Predicted)
- solubility
- DMSO : 250 mg/mL (467.85 mM; Need ultrasonic)
- pka
- 8.99±0.29(Predicted)
- form
- Solid
- color
- White to off-white
N-Bromosuccinimide Price
- Product number
- CS-0031480
- Product name
- Praliciguat
- Purity
- 98.79%
- Packaging
- 5mg
- Price
- $580
- Updated
- 2021/12/16
- Product number
- CS-0031480
- Product name
- Praliciguat
- Purity
- 98.79%
- Packaging
- 10mg
- Price
- $880
- Updated
- 2021/12/16
- Product number
- CS-0031480
- Product name
- Praliciguat
- Purity
- 98.79%
- Packaging
- 50mg
- Price
- $2300
- Updated
- 2021/12/16
- Product number
- CS-0031480
- Product name
- Praliciguat
- Purity
- 98.79%
- Packaging
- 100mg
- Price
- $3200
- Updated
- 2021/12/16
- Product number
- DC11526
- Product name
- Praliciguat
- Purity
- >98%
- Packaging
- 1g
- Price
- $3300
- Updated
- 2021/12/16
Praliciguat Chemical Properties,Usage,Production
Definition
ChEBI: Praliciguat is a member of the class of pyrazoles that is 5-fluoro-2-(1H-pyrazol-3-yl)pyrimidine which is substituted by a 2-fluorobenzyl group at position 1, 1,2-oxazol-3-yl group at position 5, and by a [3,3,3-trifluoro-2-hydroxy-2-(trifluoromethyl)propyl]nitrilo group at position 4. It is a soluble guanylate cyclase stimulator under clinical development for the treatment of heart failure with preserved ejection fraction. It has a role as a soluble guanylate cyclase activator, an anti-inflammatory agent, a vasodilator agent and an antihypertensive agent. It is a member of isoxazoles, a member of pyrazoles, an organofluorine compound, an aminopyrimidine, a tertiary alcohol, a secondary amino compound and a member of monofluorobenzenes.
Praliciguat Preparation Products And Raw materials
Raw materials
Preparation Products
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