TM2-115

Product Name: TM2-115
CAS No.: 1197196-47-6
Chemical Name: TM2-115
Synonyms: TM2-115;TM2-115, 10 mM in DMSO;[7-Benzyloxy-6-methoxy-2-(1-methyl-azepan-4-yl)- quinazolin-4-yl]-(1-methyl-piperidin-4-yl)-amine;7-(Benzyloxy)-6-methoxy-2-(4-methyl-1,4-diazepan-1-yl)-N-(1-methylpiperidin-4-yl)quinazolin-4-amine;TM2-115 [7-Benzyloxy-6-methoxy-2-(1-methyl-azepan-4-yl)- quinazolin-4-yl]-(1-methyl-piperidin-4-yl)-amine;4-Quinazolinamine, 2-(hexahydro-4-methyl-1H-1,4-diazepin-1-yl)-6-methoxy-N-(1-methyl-4-piperidinyl)-7-(phenylmethoxy)-
CBNumber: CB54668614
Molecular Formula: C28H38N6O2
Formula Weight: 490.64
MOL File: 1197196-47-6.mol

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TM2-115 Property

Boiling point:: 662.3±65.0 °C(Predicted)
Density: 1.188±0.06 g/cm3(Predicted)
solubility: DMSO: Soluble: =10 mg/ml
Ethanol: Soluble: =10 mg/ml
form: Solid
pka: 9.34±0.70(Predicted)
color: White to off-white

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

DC Chemicals

Product number: DC22873
Product name: TM2-115
Purity: >98%
Packaging: 250mg
Price: $1900
Updated: 2021/12/16

DC Chemicals

Product number: DC22873
Product name: TM2-115
Purity: >98%
Packaging: 1g
Price: $3800
Updated: 2021/12/16

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TM2-115 Chemical Properties,Usage,Production

Uses

TM2-115 inhibits malaria parasite histone methyltransferases, resulting in rapid and irreversible parasite death[1].

References

[1] Malmquist NA, et al. Small-molecule histone methyltransferase inhibitors display rapid antimalarial activity against all blood stage forms in Plasmodium falciparum. Proc Natl Acad Sci U S A. 2012 Oct 9;109(41):16708-13. DOI:10.1073/pnas.1205414109
[2] SANDEEP SUNDRIYAL. Histone lysine methyltransferase structure activity relationships that allow for segregation of G9a inhibition and anti-Plasmodium activity.[J]. MedChemComm, 2017: 1069-1092. DOI: 10.1039/c7md00052a

TM2-115 Preparation Products And Raw materials

Raw materials

Preparation Products

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TM2-115 Suppliers

China 37 United States 2 Global 39

Shanghai Lollane Biological Technology Co.,Ltd.

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TargetMol Chemicals Inc.

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1197196-47-6, TM2-115Related Search:

TMC-207

TM2-115

4-Quinazolinamine, 2-(hexahydro-4-methyl-1H-1,4-diazepin-1-yl)-6-methoxy-N-(1-methyl-4-piperidinyl)-7-(phenylmethoxy)-

TM2-115 [7-Benzyloxy-6-methoxy-2-(1-methyl-azepan-4-yl)- quinazolin-4-yl]-(1-methyl-piperidin-4-yl)-amine

[7-Benzyloxy-6-methoxy-2-(1-methyl-azepan-4-yl)- quinazolin-4-yl]-(1-methyl-piperidin-4-yl)-amine

7-(Benzyloxy)-6-methoxy-2-(4-methyl-1,4-diazepan-1-yl)-N-(1-methylpiperidin-4-yl)quinazolin-4-amine

TM2-115, 10 mM in DMSO

1197196-47-6