ChemicalBook > CAS DataBase List > TM2-115

TM2-115

Product Name
TM2-115
CAS No.
1197196-47-6
Chemical Name
TM2-115
Synonyms
TM2-115;TM2-115, 10 mM in DMSO;[7-Benzyloxy-6-methoxy-2-(1-methyl-azepan-4-yl)- quinazolin-4-yl]-(1-methyl-piperidin-4-yl)-amine;7-(Benzyloxy)-6-methoxy-2-(4-methyl-1,4-diazepan-1-yl)-N-(1-methylpiperidin-4-yl)quinazolin-4-amine;TM2-115 [7-Benzyloxy-6-methoxy-2-(1-methyl-azepan-4-yl)- quinazolin-4-yl]-(1-methyl-piperidin-4-yl)-amine;4-Quinazolinamine, 2-(hexahydro-4-methyl-1H-1,4-diazepin-1-yl)-6-methoxy-N-(1-methyl-4-piperidinyl)-7-(phenylmethoxy)-
CBNumber
CB54668614
Molecular Formula
C28H38N6O2
Formula Weight
490.64
MOL File
1197196-47-6.mol
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TM2-115 Property

Boiling point:
662.3±65.0 °C(Predicted)
Density 
1.188±0.06 g/cm3(Predicted)
solubility 
DMSO: Soluble: =10 mg/ml
Ethanol: Soluble: =10 mg/ml
form 
Solid
pka
9.34±0.70(Predicted)
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical
Product number
42901
Product name
TM2-115
Purity
≥98%
Packaging
5mg
Price
$68
Updated
2026/04/30
Cayman Chemical
Product number
42901
Product name
TM2-115
Purity
≥98%
Packaging
10mg
Price
$108
Updated
2026/04/30
Cayman Chemical
Product number
42901
Product name
TM2-115
Purity
≥98%
Packaging
25mg
Price
$218
Updated
2026/04/30
DC Chemicals
Product number
DC22873
Product name
TM2-115
Purity
>98%
Packaging
250mg
Price
$1900
Updated
2021/12/16
DC Chemicals
Product number
DC22873
Product name
TM2-115
Purity
>98%
Packaging
1g
Price
$3800
Updated
2021/12/16
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TM2-115 Chemical Properties,Usage,Production

Uses

TM2-115 inhibits malaria parasite histone methyltransferases, resulting in rapid and irreversible parasite death[1].

References

[1] Malmquist NA, et al. Small-molecule histone methyltransferase inhibitors display rapid antimalarial activity against all blood stage forms in Plasmodium falciparum. Proc Natl Acad Sci U S A. 2012 Oct 9;109(41):16708-13. DOI:10.1073/pnas.1205414109
[2] SANDEEP SUNDRIYAL. Histone lysine methyltransferase structure activity relationships that allow for segregation of G9a inhibition and anti-Plasmodium activity.[J]. MedChemComm, 2017: 1069-1092. DOI: 10.1039/c7md00052a

TM2-115 Preparation Products And Raw materials

Raw materials

Preparation Products

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TM2-115 Suppliers

Shanghai Lollane Biological Technology Co.,Ltd.
Tel
021-52996696,15000506266 15000506266
Fax
+86-21-52996696
Country
China
ProdList
4827
Advantage
55
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
Email
info@efebio.com
Country
China
ProdList
9803
Advantage
58
ShangHai Biochempartner Co.,Ltd
Tel
177-54423994 17754423994
Fax
QQ:2853530913
Email
2853530910@QQ.com
Country
China
ProdList
7999
Advantage
62
Shanghai Chaolan Chemical Technology Center
Tel
021-QQ:65489617 15618227136
Fax
21-5161 9052
Email
Sales@ATKchemical.com
Country
China
ProdList
9550
Advantage
58
MQ (shanghai) Pharmaceuticals Co., Ltd.
Tel
13761635123
Fax
1014988033@qq
Email
sales@linyuepharm.com
Country
China
ProdList
5598
Advantage
55
Dezhou LonWel Pharmaceutical Technology Co., Ltd.
Tel
13761310616
Fax
QQ: 39324283
Email
39324283@qq.com
Country
China
ProdList
1375
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354; +17819995354
Email
marketing@targetmol.com
Country
United States
ProdList
32467
Advantage
58
HANGZHOU CLAP TECHNOLOGY CO.,LTD
Tel
86-571-88216897,88216896 13588875226
Fax
86-571-88216895
Email
sales@hzclap.com
Country
CHINA
ProdList
6312
Advantage
58
Changzhou Chenhong Biotechnology Co., Ltd.
Tel
+86-0519-85788828 +86-13775037613
Email
sales@chemrenpharm.com
Country
China
ProdList
4032
Advantage
58
Suzhou youruike Chemical Pharmaceutical Technology Co., Ltd
Tel
15317229551
Fax
QQ:3607245178
Email
15151849396@163.com
Country
China
ProdList
997
Advantage
58

1197196-47-6, TM2-115Related Search:


  • TM2-115
  • 4-Quinazolinamine, 2-(hexahydro-4-methyl-1H-1,4-diazepin-1-yl)-6-methoxy-N-(1-methyl-4-piperidinyl)-7-(phenylmethoxy)-
  • TM2-115 [7-Benzyloxy-6-methoxy-2-(1-methyl-azepan-4-yl)- quinazolin-4-yl]-(1-methyl-piperidin-4-yl)-amine
  • [7-Benzyloxy-6-methoxy-2-(1-methyl-azepan-4-yl)- quinazolin-4-yl]-(1-methyl-piperidin-4-yl)-amine
  • 7-(Benzyloxy)-6-methoxy-2-(4-methyl-1,4-diazepan-1-yl)-N-(1-methylpiperidin-4-yl)quinazolin-4-amine
  • TM2-115, 10 mM in DMSO
  • 1197196-47-6