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TM2-115

Product Name
TM2-115
CAS No.
1197196-47-6
Chemical Name
TM2-115
Synonyms
TM2-115;TM2-115, 10 mM in DMSO;[7-Benzyloxy-6-methoxy-2-(1-methyl-azepan-4-yl)- quinazolin-4-yl]-(1-methyl-piperidin-4-yl)-amine;7-(Benzyloxy)-6-methoxy-2-(4-methyl-1,4-diazepan-1-yl)-N-(1-methylpiperidin-4-yl)quinazolin-4-amine;TM2-115 [7-Benzyloxy-6-methoxy-2-(1-methyl-azepan-4-yl)- quinazolin-4-yl]-(1-methyl-piperidin-4-yl)-amine;4-Quinazolinamine, 2-(hexahydro-4-methyl-1H-1,4-diazepin-1-yl)-6-methoxy-N-(1-methyl-4-piperidinyl)-7-(phenylmethoxy)-
CBNumber
CB54668614
Molecular Formula
C28H38N6O2
Formula Weight
490.64
MOL File
1197196-47-6.mol
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TM2-115 Property

Boiling point:
662.3±65.0 °C(Predicted)
Density 
1.188±0.06 g/cm3(Predicted)
solubility 
DMSO: Soluble: =10 mg/ml
Ethanol: Soluble: =10 mg/ml
form 
Solid
pka
9.34±0.70(Predicted)
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

DC Chemicals
Product number
DC22873
Product name
TM2-115
Purity
>98%
Packaging
250mg
Price
$1900
Updated
2021/12/16
DC Chemicals
Product number
DC22873
Product name
TM2-115
Purity
>98%
Packaging
1g
Price
$3800
Updated
2021/12/16
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TM2-115 Chemical Properties,Usage,Production

Uses

TM2-115 inhibits malaria parasite histone methyltransferases, resulting in rapid and irreversible parasite death[1].

References

[1] Malmquist NA, et al. Small-molecule histone methyltransferase inhibitors display rapid antimalarial activity against all blood stage forms in Plasmodium falciparum. Proc Natl Acad Sci U S A. 2012 Oct 9;109(41):16708-13. DOI:10.1073/pnas.1205414109
[2] SANDEEP SUNDRIYAL. Histone lysine methyltransferase structure activity relationships that allow for segregation of G9a inhibition and anti-Plasmodium activity.[J]. MedChemComm, 2017: 1069-1092. DOI: 10.1039/c7md00052a

TM2-115 Preparation Products And Raw materials

Raw materials

Preparation Products

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TM2-115 Suppliers

China 37 United States 2 Global 39
TargetMol Chemicals Inc.
Tel
+1-781-999-5354; +17819995354
Email
marketing@targetmol.com
Country
United States
ProdList
32435
Advantage
58
Aladdin Scientific
Tel
Email
tp@aladdinsci.com
Country
United States
ProdList
52923
Advantage
58

1197196-47-6, TM2-115Related Search:

TMC-207

  • TM2-115
  • 4-Quinazolinamine, 2-(hexahydro-4-methyl-1H-1,4-diazepin-1-yl)-6-methoxy-N-(1-methyl-4-piperidinyl)-7-(phenylmethoxy)-
  • TM2-115 [7-Benzyloxy-6-methoxy-2-(1-methyl-azepan-4-yl)- quinazolin-4-yl]-(1-methyl-piperidin-4-yl)-amine
  • [7-Benzyloxy-6-methoxy-2-(1-methyl-azepan-4-yl)- quinazolin-4-yl]-(1-methyl-piperidin-4-yl)-amine
  • 7-(Benzyloxy)-6-methoxy-2-(4-methyl-1,4-diazepan-1-yl)-N-(1-methylpiperidin-4-yl)quinazolin-4-amine
  • TM2-115, 10 mM in DMSO
  • 1197196-47-6