NCT-505

Product Name: NCT-505
CAS No.: 2231079-74-4
Chemical Name: NCT-505
Synonyms: NCT-505 free base;NCT-505, 10 mM in DMSO;inhibit,Aldehyde Dehydrogenase (ALDH),NCT-505,Inhibitor,NCT505,NCT 505;1-(6-Fluoro-3-(4-(methylsulfonyl)piperazine-1-carbonyl)quinolin-4-yl)-4-phenylpiperidine-4-carbonitrile;4-Piperidinecarbonitrile, 1-[6-fluoro-3-[[4-(methylsulfonyl)-1-piperazinyl]carbonyl]-4-quinolinyl]-4-phenyl-;1-(6-Fluoro-3-(4-(methylsulfonyl)piperazine-1-carbonyl)quinolin-4-yl)-4-phenylpiperidine-4-carbonitrile , NCT-505
CBNumber: CB54672251
Molecular Formula: C27H28FN5O3S
Formula Weight: 521.61
MOL File: 2231079-74-4.mol

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NCT-505 Property

storage temp.: Store at -20°C
solubility: Soluble in DMSO
form: Solid
color: White to off-white

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

A1 Biochem Labs

Product number: 6586436
Product name: 1-(6-Fluoro-3-(4-(methylsulfonyl)piperazine-1-carbonyl)quinolin-4-yl)-4-phenylpiperidine-4-carbonitrile
Purity: 95%
Packaging: 1g
Price: $1500
Updated: 2021/12/16

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NCT-505 Chemical Properties,Usage,Production

Description

NCT-505 is an Orally Bioavailable aldehyde Dehydrogenase 1A1 (ALDH1A1) Inhibitor with Potent Cellular Activity (IC50 = 7 nM). NCT-505 demonstrated target engagement in a cellular thermal shift assay (CETSA), inhibited the formation of 3D spheroid cultures of OV-90 cancer cells, and potentiated the cytotoxicity of paclitaxel in SKOV-3-TR, a paclitaxel resistant ovarian cancer cell line. NCT-505 also exhibit high specificity over other ALDH isozymes and unrelated dehydrogenases.

NCT-505 Preparation Products And Raw materials

Raw materials

Preparation Products

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NCT-505 Suppliers

China 9 United States 3 Global 12

Fan De(Beijing) Biotechnology Co., Ltd.

Tel: 15911056312
Email: liming@bio-fount.com
Country: China
ProdList: 9729
Advantage: 58

DC Chemicals

Tel: 021-58447131 13564518121
Email: sales@dcchemicals.com
Country: China
ProdList: 9409
Advantage: 58

Bide Pharmatech Ltd.

Tel: 400-1647117 13681763483
Email: product02@bidepharm.com
Country: China
ProdList: 62075
Advantage: 58

TargetMol Chemicals Inc.

Tel: 4008200310
Email: marketing@tsbiochem.com
Country: China
ProdList: 24644
Advantage: 58

Shanghai Yifei Biotechnology Co. , Ltd.

Tel: 021-65675885 18964387627
Email: customer_service@efebio.com
Country: China
ProdList: 11974
Advantage: 58

RD International Technology Co., Limited

Tel: 18024082417
Email: market@ubiochem.com
Country: China
ProdList: 9266
Advantage: 58

Changzhou Yourui Pharmaceutical Technology Co., Ltd

Tel: 18168818882 18168818882
Email: 877458914@qq.com
Country: China
ProdList: 2728
Advantage: 58

Tel
Email: sangon@qq.com
Country: CHINA
ProdList: 47239
Advantage: 58

Proteintech China

Tel: --
Fax: --
Email: Proteintech-CN@ptglab.com
Country: CHINA
ProdList: 6290
Advantage: 58

2231079-74-4, NCT-505Related Search:

NCT-505 free base

4-Piperidinecarbonitrile, 1-[6-fluoro-3-[[4-(methylsulfonyl)-1-piperazinyl]carbonyl]-4-quinolinyl]-4-phenyl-

1-(6-Fluoro-3-(4-(methylsulfonyl)piperazine-1-carbonyl)quinolin-4-yl)-4-phenylpiperidine-4-carbonitrile

inhibit,Aldehyde Dehydrogenase (ALDH),NCT-505,Inhibitor,NCT505,NCT 505

1-(6-Fluoro-3-(4-(methylsulfonyl)piperazine-1-carbonyl)quinolin-4-yl)-4-phenylpiperidine-4-carbonitrile , NCT-505

NCT-505, 10 mM in DMSO

2231079-74-4

C27H28FN5O3S