BI-3812

Product Name: BI-3812
CAS No.: 2166387-64-8
Chemical Name: BI-3812
Synonyms: CPD1815;BI-3812;BI3812;BI 3812;BI-3812/CPD1815;BI-3812, 10 mM in DMSO;BI 3812,BI3812,BI-3812,Inhibitor,inhibit,Bcl-2 Family;1-(5-Chloro-4-((8-methoxy-1-methyl-3-(2-(methylamino)-2-oxoethoxy)-2-oxo-1,2-dihydroquinolin-6-yl)amino)pyrimidin-2-yl)-N,N-dimethylpiperidine-4-carboxamide;4-Piperidinecarboxamide, 1-[5-chloro-4-[[1,2-dihydro-8-methoxy-1-methyl-3-[2-(methylamino)-2-oxoethoxy]-2-oxo-6-quinolinyl]amino]-2-pyrimidinyl]-N,N-dimethyl-
CBNumber: CB54675308
Molecular Formula: C26H32ClN7O5
Formula Weight: 558.03
MOL File: 2166387-64-8.mol

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BI-3812 Property

Density: 1.40±0.1 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMSO:22.92(Max Conc. mg/mL);41.07(Max Conc. mM)
form: Solid
pka: 14.73±0.46(Predicted)
color: Off-white to pink

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML4033
Product name: BI-3812
Purity: ≥98% (HPLC)
Packaging: 1 unit
Price: $303.05
Updated: 2025/07/31

DC Chemicals

Product number: DC23310
Product name: BI-3812
Purity: >98%
Packaging: 250mg
Price: $1700
Updated: 2021/12/16

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BI-3812 Chemical Properties,Usage,Production

Uses

BI-3812 is a highly efficient BCL6 inhibitor that is capable of suppressing the BTB domain of BCL6, with an IC50 value of ≤ 3 nM, exhibiting antitumor activity[1].

Biological Activity

BI-3812 is a potent BCL6 inhibitor with IC50 less than 3 nM.

in vivo

BI-3812 is a BCL6 inhibitor, with an IC ₅₀ of ≤3 nM. BI-3812 shows an IC ₅₀ of 40 nM for the cellular BCL6.

target

Target	Value
BCL6 (Cell-free assay)	3 nM

References

[1] Kerres N, et al. Chemically Induced Degradation of the Oncogenic Transcription Factor BCL6. Cell Rep. 2017 Sep 19;20(12):2860-2875. DOI:10.1016/j.celrep.2017.08.081

BI-3812 Preparation Products And Raw materials

Raw materials

Preparation Products

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BI-3812 Suppliers

China 59 United States 5 Global 64

BOC Sciences

Tel: 1-631-485-4226; 16314854226
Email: info@bocsci.com
Country: United States
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ShangHai Caerulum Pharma Discovery Co., Ltd.

Tel: 18149758185
Email: sales-cpd@caerulumpharma.com
Country: China
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Sichuan Wei Keqi Biological Technology Co., Ltd.

Tel: 028-81700200 18116577057
Fax: 028-81705658
Email: 3003855609@qq.com
Country: China
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Finetech Industry Limited

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Email: sales@finetechnology-ind.com
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Shanghai Lollane Biological Technology Co.,Ltd.

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Fax: +86-21-52996696
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Twochem Co.Ltd

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Shanghai YuanYe Biotechnology Co., Ltd.

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Email: 3008007409@qq.com
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ShangHai Biochempartner Co.,Ltd

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Beijing Solarbio Science & Tecnology Co., Ltd.

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Beijing Jin Ming Biotechnology Co., Ltd.

Tel: 010-60605840 18892239720
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Email: psaitong@jm-bio.com
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2166387-64-8, BI-3812Related Search:

BI3812;BI 3812

BI-3812

CPD1815

1-(5-Chloro-4-((8-methoxy-1-methyl-3-(2-(methylamino)-2-oxoethoxy)-2-oxo-1,2-dihydroquinolin-6-yl)amino)pyrimidin-2-yl)-N,N-dimethylpiperidine-4-carboxamide

4-Piperidinecarboxamide, 1-[5-chloro-4-[[1,2-dihydro-8-methoxy-1-methyl-3-[2-(methylamino)-2-oxoethoxy]-2-oxo-6-quinolinyl]amino]-2-pyrimidinyl]-N,N-dimethyl-

BI-3812/CPD1815

BI 3812,BI3812,BI-3812,Inhibitor,inhibit,Bcl-2 Family

BI-3812, 10 mM in DMSO

2166387-64-8

C26H32ClN7O5

APIs