ChemicalBook > CAS DataBase List > Isoviolanthin

Isoviolanthin

Product Name: Isoviolanthin
CAS No.: 40788-84-9
Chemical Name: Isoviolanthin
Synonyms: Isoviolanthin;Isoviolanthin, 10 mM in DMSO;4H-1-Benzopyran-4-one, 6-(6-deoxy-α-L-mannopyranosyl)-8-β-D-glucopyranosyl-5,7-dihydroxy-2-(4-hydroxyphenyl)-;TGF-beta/Smad,Transforming growth factor beta,normal liver LO2 cells,TGF-β1 EMT,Isoviolanthin,hepatocellular carcinoma cells cytotoxic effects,Inhibitor,inhibit;5,7-Dihydroxy-2-(4-hydroxyphenyl)-8-((2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)-6-((2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)-4H-chromen-4-one
CBNumber: CB54680225
Molecular Formula: C27H30O14
Formula Weight: 578.52
MOL File: 40788-84-9.mol

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Isoviolanthin Property

Boiling point:: 925.3±65.0 °C(Predicted)
Density: 1.703±0.06 g/cm3(Predicted)
pka: 5.70±0.40(Predicted)
form: Solid
color: Light yellow to yellow

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene

Product number: CS-0100508
Product name: Isoviolanthin
Packaging: 5mg
Price: $269
Updated: 2021/12/16

ChemScene

Product number: CS-0100508
Product name: Isoviolanthin
Packaging: 10mg
Price: $457
Updated: 2021/12/16

Biorbyt Ltd

Product number: orb594450
Product name: Isoviolanthin
Packaging: 20mg
Price: $571.2
Updated: 2021/12/16

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Isoviolanthin Chemical Properties,Usage,Production

Uses

Isoviolanthin, a flavonoid glycoside, could markedly inhibit TGF-β1-mediated migration and invasion by deactivating epithelial-mesenchymal transition (EMT) via the TGF-β/Smad and PI3K/Akt/mTOR pathways in HCC cells. Isoviolanthin exhibits no cytotoxic effects on normal liver LO2 cells[1].

References

[1] Xing S, et al. Isoviolanthin Extracted from Dendrobium officinale Reverses TGF-β1-Mediated Epithelial?Mesenchymal Transition in Hepatocellular Carcinoma Cells via Deactivating the TGF-β/Smad and PI3K/Akt/mTOR Signaling Pathways. Int J Mol Sci. 2018 May 23;19(6). DOI:10.3390/ijms19061556

Isoviolanthin Preparation Products And Raw materials

Raw materials

Preparation Products

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Isoviolanthin

4H-1-Benzopyran-4-one, 6-(6-deoxy-α-L-mannopyranosyl)-8-β-D-glucopyranosyl-5,7-dihydroxy-2-(4-hydroxyphenyl)-

TGF-beta/Smad,Transforming growth factor beta,normal liver LO2 cells,TGF-β1 EMT,Isoviolanthin,hepatocellular carcinoma cells cytotoxic effects,Inhibitor,inhibit

5,7-Dihydroxy-2-(4-hydroxyphenyl)-8-((2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)-6-((2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)-4H-chromen-4-one

Isoviolanthin, 10 mM in DMSO

40788-84-9