Z-DL-LYS(Z)-OH

Product Name: Z-DL-LYS(Z)-OH
CAS No.: 55592-85-3
Chemical Name: Z-DL-LYS(Z)-OH
Synonyms: Z-DL-LYS(D)-OH;Z-DL-LYS(Z)-OH;CBZ-DL-LYS(Z)-OH;Z-DL-LYSINE(Z)-OH;Cbz-DL-Lys(Cbz)-OH;nα,nε-di-z-dl-lysine;2,6-Bis(((benzyloxy);N2,N6-Bis-Cbz-DL-lysine;Z-DL-Lys(Z)-OH;Z-DL-Lys(Z)-OH >=98.0% (TLC)
CBNumber: CB5468186
Molecular Formula: C22H26N2O6
Formula Weight: 414.45
MOL File: 55592-85-3.mol

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Z-DL-LYS(Z)-OH Property

Melting point:: 90-95 °C (lit.)
Boiling point:: 659.0±55.0 °C(Predicted)
Density: 1.238±0.06 g/cm3(Predicted)
storage temp.: Sealed in dry,2-8°C
pka: 3.97±0.21(Predicted)
form: solid
Appearance: White to off-white Solid
BRN: 2027663
Major Application: peptide synthesis
InChI: 1S/C22H26N2O6/c25-20(26)19(24-22(28)30-16-18-11-5-2-6-12-18)13-7-8-14-23-21(27)29-15-17-9-3-1-4-10-17/h1-6,9-12,19H,7-8,13-16H2,(H,23,27)(H,24,28)(H,25,26)
InChIKey: BLZXFNUZFTZCFD-UHFFFAOYSA-N
SMILES: OC(=O)C(CCCCNC(=O)OCc1ccccc1)NC(=O)OCc2ccccc2

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Safety

Safety Statements: 22-24/25
WGK Germany: 3
Storage Class: 11 - Combustible Solids

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H411Toxic to aquatic life with long lasting effects

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P273Avoid release to the environment.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P330Rinse mouth.

P391Collect spillage. Hazardous to the aquatic environment

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 96837
Product name: Z-DL-Lys(Z)-OH
Purity: ≥98.0% (TLC)
Packaging: 5g
Price: $52
Updated: 2023/01/07

TRC

Product number: L113493
Product name: Z-DL-LYS(Z)-OH
Packaging: 500mg
Price: $75
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: AAA0003881
Product name: Z-DL-LYS(Z)-OH
Purity: 95.00%
Packaging: 1G
Price: $258.3
Updated: 2021/12/16

Activate Scientific

Product number: AS102784
Product name: N2,N6-Bis-Cbz-DL-lysine
Purity: 95%
Packaging: 25g
Price: $274
Updated: 2021/12/16

AK Scientific

Product number: 3919AL
Product name: Z-Dl-Lys(Z)-OH
Packaging: 1g
Price: $66
Updated: 2021/12/16

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Z-DL-LYS(Z)-OH Chemical Properties,Usage,Production

Uses

peptide synthesis

reaction suitability

reaction type: solution phase peptide synthesis

Synthesis

32302-83-3

501-53-1

55592-85-3

GENERAL METHOD: 2-Amino-6-(((benzyloxy)carbonyl)amino)hexanoic acid (5.0 g, 30 mmol, 1.0 eq.) was dissolved in a solution of NaOH (2M, 50 mL) and stirred at 0°C and under nitrogen protection. Benzyl chloroformate (4.3 mL, 30 mmol, 1.0 eq.) was dissolved in toluene (5 mL) followed by addition of NaOH (4M, 5 mL) solution. The reaction mixture was stirred vigorously at room temperature for 30 minutes. Upon completion of the reaction, it was diluted with water (50 mL) and extracted with diethyl ether (2 x 50 mL). After combining the organic phases, it was cooled to 0°C and acidified with concentrated hydrochloric acid to pH 1, at which point a white solid precipitated. The solid product was collected by filtration. The resulting solid was dissolved in dichloromethane (200 mL), and the organic layer was washed with brine (50 mL), followed by drying with anhydrous magnesium sulfate, and finally concentrated under vacuum to obtain the target product Cbz-N'-Cbz-DL-lysine.

References

[1] European Journal of Medicinal Chemistry, 2014, vol. 84, # C, p. 584 - 594

Z-DL-LYS(Z)-OH Preparation Products And Raw materials

Raw materials

Preparation Products

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Z-DL-LYS(Z)-OH Suppliers

China 42 India 1 Japan 1 Switzerland 1 United Kingdom 1 United States 5 Global 51

Energy Chemical

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Guangzhou Isun Pharmaceutical Co., Ltd

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Bide Pharmatech Ltd.

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Sigma-Aldrich

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Shanghai GL Peptide Ltd.

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Nanjing Peptide Biotech Ltd.

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55592-85-3, Z-DL-LYS(Z)-OHRelated Search:

N-CARBOBENZOXY-DL-PHENYLALANINE N-CARBOBENZOXY-DL-NORVALINE N-CARBOBENZOXY-DL-SERINE 1-[(BENZYLOXY)CARBONYL]PYRROLIDINE-2-CARBOXYLIC ACID N-CBZ-DL-HISTIDINE Z-DL-Ser(Bzl)-OH N-CARBOBENZOXY-DL-VALINE Z-DL-PHE(4-CL)-OH N-CARBOBENZOXY-DL-METHIONINE N-CBZ-DL-TRYPTOPHAN N-CARBOBENZOXY-DL-LEUCINE DL-Lysine Z-Lys(Z)-OH N,N'-Dibenzyloxycarbonyl-D-lysine AC-DL-LYS (AC)-OH Z-DL-LYS(Z)-OH Z-LYS(Z)-OSU Z-LYS(Z)-ONP

N-ALPHA,N-EPSILON-DI-Z-DL-LYSINE

N-ALPHA-N-EPSILON-DICARBOBENZOXY-DL-LYSINE

N-ALPHA,EPSILON-BIS-Z-DL-LYSINE

Z-DL-LYS(D)-OH

Z-DL-LYSINE(Z)-OH

Z-DL-LYS(Z)-OH

nα,nε-di-z-dl-lysine

N,N''-DICARBOBENZYLOXY-DL-LYSINE)

Nα,Nε-Di-Z-DL-lysine, Nα,Nε-di-Z-DL-lysine

2,6-Bis(((benzyloxy)carbonyl)aMino)hexanoic acid

Z-DL-Lys(Z)-OH >=98.0% (TLC)

Cbz-DL-Lys(Cbz)-OH

2,6-Bis(((benzyloxy)

2,6-di{[(benzyloxy)carbonyl]amino}hexanoic acid

Lysine, N2,N6-bis[(phenylmethoxy)carbonyl]-

N-α,N-ε-Di(carbobenzoxy)-DL-lysine

N2,N6-Bis-Cbz-DL-lysine

CBZ-DL-LYS(Z)-OH

Z-<sc>DL</sc>-Lys(Z)-OH

55592-85-3

Peptide Synthesis

Specialty Synthesis

Lysine

Amino Acid Derivatives