ChemicalBook > CAS DataBase List > AT6
AT6
- Product Name
- AT6
- CAS No.
- 2098836-50-9
- Chemical Name
- AT6
- Synonyms
- AT6;(2S,4R)-1-[(2R)-3-({2-[2-(2-{2-[(9S)-7-(4-chlorophenyl)-4,5,13-trimethyl-3-thia-1,8,11,12-tetraazatricyclo[8.3.0.02,?]trideca-2(6),4,7,10,12-pentaen-9-yl]acetamido}ethoxy)ethoxy]ethyl}sulfanyl)-2-acetamido-3-methylbutanoyl]-4-hydroxy-N-{[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl}pyrrolidine-2-carboxamide
- CBNumber
- CB54718704
- Molecular Formula
- C48H58ClN9O7S3
- Formula Weight
- 1004.68
- MOL File
- 2098836-50-9.mol
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AT6 Property
- Density
- 1.41±0.1 g/cm3(Predicted)
- storage temp.
- Store at -20°C, protect from light, stored under nitrogen
- solubility
- Soluble in DMSO
- form
- Solid
- pka
- 14.05±0.40(Predicted)
- color
- White to off-white
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N-Bromosuccinimide Price
A2B
- Product number
- AX64029
- Product name
- AT6
- Packaging
- 1mg
- Price
- $335
- Updated
- 2021/12/16
A2B
- Product number
- AX64029
- Product name
- AT6
- Packaging
- 5mg
- Price
- $685
- Updated
- 2021/12/16
A2B
- Product number
- AX64029
- Product name
- AT6
- Packaging
- 10mg
- Price
- $1085
- Updated
- 2021/12/16
A2B
- Product number
- AX64029
- Product name
- AT6
- Packaging
- 25mg
- Price
- $2185
- Updated
- 2021/12/16
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AT6 Chemical Properties,Usage,Production
Uses
AT6 is a PROTAC AT1 analogue, which is a PROTAC connected by ligands for von Hippel-Lindau and BRD4 with highly selectivity to bromodomain (Brd4).
References
[1] Gadd MS, et al. Structural basis of PROTAC cooperative recognition for selective protein degradation. Nat Chem Biol. 2017 May;13(5):514-521. DOI:10.1038/nchembio.2329
AT6 Preparation Products And Raw materials
Raw materials
Preparation Products
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AT6 Suppliers
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