ChemicalBook > CAS DataBase List > 1-[(benzyloxy)carbonyl]-4-ethyl-2,5-dihydro-1H-pyrrole-3-carboxylic acid

1-[(benzyloxy)carbonyl]-4-ethyl-2,5-dihydro-1H-pyrrole-3-carboxylic acid

Product Name
1-[(benzyloxy)carbonyl]-4-ethyl-2,5-dihydro-1H-pyrrole-3-carboxylic acid
CAS No.
1869118-25-1
Chemical Name
1-[(benzyloxy)carbonyl]-4-ethyl-2,5-dihydro-1H-pyrrole-3-carboxylic acid
Synonyms
Upadacitinib Impurity 41;Impurities in Upatinib 17;1-[(benzyloxy)carbonyl]-4-ethyl-2,5-dihydro-1H-pyrrole-3-carboxylic acid;1H-Pyrrole-1,3-dicarboxylic acid, 4-ethyl-2,5-dihydro-, 1-(phenylmethyl) ester
CBNumber
CB54747852
Molecular Formula
C15H17NO4
Formula Weight
275.3
MOL File
1869118-25-1.mol
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1-[(benzyloxy)carbonyl]-4-ethyl-2,5-dihydro-1H-pyrrole-3-carboxylic acid Property

Boiling point:
452.3±45.0 °C(Predicted)
Density 
1.267±0.06 g/cm3(Predicted)
pka
4.28±0.20(Predicted)
InChI
InChI=1S/C15H17NO4/c1-2-12-8-16(9-13(12)14(17)18)15(19)20-10-11-6-4-3-5-7-11/h3-7H,2,8-10H2,1H3,(H,17,18)
InChIKey
HFBYGZWWAMZBID-UHFFFAOYSA-N
SMILES
N1(C(OCC2=CC=CC=C2)=O)CC(CC)=C(C(O)=O)C1
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P330Rinse mouth.

P501Dispose of contents/container to..…

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1-[(benzyloxy)carbonyl]-4-ethyl-2,5-dihydro-1H-pyrrole-3-carboxylic acid Chemical Properties,Usage,Production

Uses

1-[(benzyloxy)carbonyl]-4-ethyl-2,5-dihydro-1H-pyrrole-3-carboxylic acid is a pharmaceutical intermediate compound used in the synthesis of Upadacitinib, a Janus kinase (JAK) inhibitor approved by the FDA for the treatment of various chronic inflammatory conditions such as moderate-to-severe rheumatoid arthritis (RA), psoriatic arthritis, atopic dermatitis, ankylosing spondylitis, Crohn's disease, and ulcerative colitis.

1-[(benzyloxy)carbonyl]-4-ethyl-2,5-dihydro-1H-pyrrole-3-carboxylic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 1-[(benzyloxy)carbonyl]-4-ethyl-2,5-dihydro-1H-pyrrole-3-carboxylic acid manufacturers

Anhui Dexinjia Biopharm Co., Ltd
Product
1-[(benzyloxy)carbonyl]-4-ethyl-2,5-dihydro-1H-pyrrole-3-carboxylic acid 1869118-25-1
Price
US $100.00-10.00/KG
Min. Order
1KG
Purity
less more than 98%
Supply Ability
20tons
Release date
2024-05-13
S&Y Biochem Co.,Ltd
Product
1-[(benzyloxy)carbonyl]-4-ethyl-2,5-dihydro-1H-pyrrole-3-carboxylic acid 1869118-25-1
Price
US $1.00/kg
Min. Order
1kg
Purity
99
Supply Ability
100
Release date
2024-08-01
ShenZhen H&D Pharmaceutical Technology Co., LTD
Product
Upadacitinib Impurity 41 1869118-25-1
Price
US $0.00/mg
Min. Order
10mg
Purity
0.98
Supply Ability
10g
Release date
2024-03-28

1869118-25-1, 1-[(benzyloxy)carbonyl]-4-ethyl-2,5-dihydro-1H-pyrrole-3-carboxylic acidRelated Search:


  • 1-[(benzyloxy)carbonyl]-4-ethyl-2,5-dihydro-1H-pyrrole-3-carboxylic acid
  • 1H-Pyrrole-1,3-dicarboxylic acid, 4-ethyl-2,5-dihydro-, 1-(phenylmethyl) ester
  • Impurities in Upatinib 17
  • Upadacitinib Impurity 41
  • 1869118-25-1