RMI 10874
- Product Name
- RMI 10874
- CAS No.
- 38020-45-0
- Chemical Name
- RMI 10874
- Synonyms
- RMI 10874;9H-Xanthen-9-one, 3,6-bis[2-(dimethylamino)ethoxy]-
- CBNumber
- CB54797099
- Molecular Formula
- C21H26N2O4
- Formula Weight
- 370.44
- MOL File
- 38020-45-0.mol
RMI 10874 Property
- storage temp.
- Store at -20°C
- solubility
- Soluble in DMSO
RMI 10874 Chemical Properties,Usage,Production
Uses
RMI 10874, is a Tilorone (T4408000 analogue, which is an orally active, interferon-inducing antiviral agent.
in vivo
The effect of RMI 10874 (RMI 10,874DA) in the abrogation of the metastatic spread of tumor cells is studied. Pre-treatment of BALB/c mice with the RMI 10,874DA completely eliminates lung colonization of an H-2-negative (GR9.B9) MCA-induced fibrosarcoma clone in an experimental metastasis assay[1]. The effect of a tilorone analogue (RMI 10,874DA) and anti-asialo GM1 serum is studied on the survival of BALB/c and C57B1/6 mice after i.v. injections of different syngeneic murine tumor cells. Natural killer (NK) cell activation in vivo by RMI 10874 prolongs survival and inhibits metastasis formation in mice, even when pretreatment consists of a single dose of the analogue[2]. Tilorone is a small-molecule, orally bioavailable drug that is used clinically as an antiviral[3].
RMI 10874 Preparation Products And Raw materials
Raw materials
Preparation Products
RMI 10874 Suppliers
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- 0755-85201366 18938635012
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- 0755-85201366
- sales@regentsciences.com
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- China
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- 9750
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- +1-781-999-5354; +17819995354
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- United States
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- China
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- 4008200310
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- China
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- 400-025-6535
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- Country
- China
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- Tel
- +17819995354
- marketing@targetmol.com
- Country
- United States
- ProdList
- 19961
- Advantage
- 58
- Tel
- +1-781-999-5354;
- support@targetmol.com
- Country
- United States
- ProdList
- 39035
- Advantage
- 58