ATR inhibitor 1

Product Name: ATR inhibitor 1
CAS No.: 1613200-51-3
Chemical Name: ATR inhibitor 1
Synonyms: M-1774;Tuvusertib;ATR inhibitor 1;M1774|||ATR inhibitor 1;Tuvusertib, 10 mM in DMSO;2-Amino-6-fluoro-N-[5-fluoro-4-(1-methyl-1H-imidazol-5-yl)-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;Pyrazolo[1,5-a]pyrimidine-3-carboxamide, 2-amino-6-fluoro-N-[5-fluoro-4-(1-methyl-1H-imidazol-5-yl)-3-pyridinyl]-
CBNumber: CB54805789
Molecular Formula: C16H12F2N8O
Formula Weight: 370.32
MOL File: 1613200-51-3.mol

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ATR inhibitor 1 Property

Density: 1.68±0.1 g/cm3(Predicted)
storage temp.: Store at -20°C
pka: 6.48±0.46(Predicted)
form: Solid
color: Light yellow to yellow

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Hazard and Precautionary Statements (GHS)

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ATR inhibitor 1 Chemical Properties,Usage,Production

Uses

Tuvusertib (M1774; ATR inhibitor 1) is a selective and orally active ATR inhibitor extracted from patent WO2015187451A1, compound I-l, with a Ki value below 1 μΜ[1].

References

[1] Nadia AHMAD, et al. Radiolabelled derivatives of a 2-amino-6-fluoro-n-[5-fluoro-pyridin-3-yl]- pyrazolo[1,5-a]pyrimidin-3-carboxamide compound useful as atr kinase inhibitor, the preparation of said compound and different solid forms thereof. WO2015187451A1
[2] Lin Li, et al. Non-canonical role for the ataxia-telangiectasia-Rad3 pathway in STAT3 activation in human multiple myeloma cells DOI:10.1007/s13402-023-00817-6

ATR inhibitor 1 Preparation Products And Raw materials

Raw materials

Preparation Products

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ATR inhibitor 1 Suppliers

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1613200-51-3, ATR inhibitor 1Related Search:

ATR inhibitor 1

Tuvusertib

Pyrazolo[1,5-a]pyrimidine-3-carboxamide, 2-amino-6-fluoro-N-[5-fluoro-4-(1-methyl-1H-imidazol-5-yl)-3-pyridinyl]-

M-1774

M1774|||ATR inhibitor 1

Tuvusertib, 10 mM in DMSO

2-Amino-6-fluoro-N-[5-fluoro-4-(1-methyl-1H-imidazol-5-yl)-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide

1613200-51-3