ChemicalBook > CAS DataBase List > UAMC-3203

UAMC-3203

Product Name
UAMC-3203
CAS No.
2271358-64-4
Chemical Name
UAMC-3203
Synonyms
UAMC-3203;(S)-L-Cystine-;UAMC3203;UAMC 3203;inhibit,Ferroptosis,Inhibitor,UAMC-3203;Benzenesulfonamide, 4-(cyclohexylamino)-3-[(phenylmethyl)amino]-N-[2-(1-piperazinyl)ethyl]-
CBNumber
CB54843929
Molecular Formula
C25H37N5O2S
Formula Weight
471.66
MOL File
2271358-64-4.mol
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UAMC-3203 Property

Boiling point:
668.3±65.0 °C(Predicted)
Density 
1.214±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
Ethanol: Soluble
form 
A crystalline solid
pka
12.27±0.50(Predicted)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H400Very toxic to aquatic life

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P273Avoid release to the environment.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P330Rinse mouth.

P391Collect spillage. Hazardous to the aquatic environment

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical
Product number
26525
Product name
UAMC-3203
Packaging
1mg
Price
$32
Updated
2024/03/01
Cayman Chemical
Product number
26525
Product name
UAMC-3203
Packaging
5mg
Price
$109
Updated
2024/03/01
Cayman Chemical
Product number
26525
Product name
UAMC-3203
Purity
≥98%
Packaging
10mg
Price
$153
Updated
2024/03/01
Cayman Chemical
Product number
26525
Product name
UAMC-3203
Purity
≥98%
Packaging
25mg
Price
$305
Updated
2024/03/01
Cayman Chemical
Product number
26525
Product name
UAMC-3203
Packaging
500μg
Price
$27
Updated
2021/12/16
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UAMC-3203 Chemical Properties,Usage,Production

Biological Activity

UAMC-3203 is a ferroptosis inhibitor with IC50 of 10 nM in IMR-32 neuroblastoma cells.

in vitro

UAMC-3203 was incubated with human microsomes or rat microsomes, and the T 1/2 were 20.5 h and 16.5 h, respectively. When co-incubated with mouse microsomes, UAMC-3203 showed relatively poor stability, with a T 1/2 of 3.46 h.

in vivo

In mice, UAMC-3203 can significantly reduce the plasma concentration of lactate dehydrogenase. After administration, it is rapidly removed from the blood and enters various tissues. Significant levels of UAMC-3203 were detected in the tissues tested, such as liver, kidney and lung.

target

< td style="border-bottom: 1px dotted #ccc;padding: 5px;"> 10 nM
TargetValue
Ferroptosis
(IMR-32 neuroblastoma cells)

UAMC-3203 Preparation Products And Raw materials

Raw materials

Preparation Products

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UAMC-3203 Suppliers

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2271358-64-4, UAMC-3203Related Search:


  • UAMC3203;UAMC 3203
  • UAMC-3203
  • inhibit,Ferroptosis,Inhibitor,UAMC-3203
  • Benzenesulfonamide, 4-(cyclohexylamino)-3-[(phenylmethyl)amino]-N-[2-(1-piperazinyl)ethyl]-
  • (S)-L-Cystine-
  • 2271358-64-4