ChemicalBook > CAS DataBase List > Aumitin
Aumitin
- Product Name
- Aumitin
- CAS No.
- 946293-78-3
- Chemical Name
- Aumitin
- Synonyms
- Aumitin;inhibit,Autophagy,Aumitin,Inhibitor;Benzamide, 2-chloro-N-[4-[[4-methyl-6-(phenylamino)-2-pyrimidinyl]amino]phenyl]-
- CBNumber
- CB54844496
- Molecular Formula
- C24H20ClN5O
- Formula Weight
- 429.9
- MOL File
- 946293-78-3.mol
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Aumitin Property
- Density
- 1.364±0.06 g/cm3(Predicted)
- pka
- 12.36±0.70(Predicted)
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N-Bromosuccinimide Price
DC Chemicals
- Product number
- DC21865
- Product name
- Aumitin
- Purity
- >98%
- Packaging
- 250mg
- Price
- $1600
- Updated
- 2021/12/16
DC Chemicals
- Product number
- DC21865
- Product name
- Aumitin
- Purity
- >98%
- Packaging
- 1g
- Price
- $3200
- Updated
- 2021/12/16
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Aumitin Chemical Properties,Usage,Production
Biological Activity
Aumitin is a diaminopyrimidine-based autophagy inhibitor which inhibits mitochondrial respiration by targeting complex I. Aumitin inhibits starvation- and rapamycin induced autophagy dose dependently with IC50s of 0.12 μM and 0.24 μM, respectively[1].
References
[1]. Robke L, et al. Discovery of the novel autophagy inhibitor aumitin that targets mitochondrial complex I. Chem Sci. 2018 Feb 26;9(11):3014-3022.
Aumitin Preparation Products And Raw materials
Raw materials
Preparation Products
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