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Aumitin

Product Name
Aumitin
CAS No.
946293-78-3
Chemical Name
Aumitin
Synonyms
Aumitin;inhibit,Autophagy,Aumitin,Inhibitor;Benzamide, 2-chloro-N-[4-[[4-methyl-6-(phenylamino)-2-pyrimidinyl]amino]phenyl]-
CBNumber
CB54844496
Molecular Formula
C24H20ClN5O
Formula Weight
429.9
MOL File
946293-78-3.mol
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Aumitin Property

Density 
1.364±0.06 g/cm3(Predicted)
pka
12.36±0.70(Predicted)
form 
Solid
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

DC Chemicals
Product number
DC21865
Product name
Aumitin
Purity
>98%
Packaging
250mg
Price
$1600
Updated
2021/12/16
DC Chemicals
Product number
DC21865
Product name
Aumitin
Purity
>98%
Packaging
1g
Price
$3200
Updated
2021/12/16
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Aumitin Chemical Properties,Usage,Production

Biological Activity

Aumitin is a diaminopyrimidine-based autophagy inhibitor which inhibits mitochondrial respiration by targeting complex I. Aumitin inhibits starvation- and rapamycin induced autophagy dose dependently with IC50s of 0.12 μM and 0.24 μM, respectively[1].

References

[1]. Robke L, et al. Discovery of the novel autophagy inhibitor aumitin that targets mitochondrial complex I. Chem Sci. 2018 Feb 26;9(11):3014-3022.

Aumitin Preparation Products And Raw materials

Raw materials

Preparation Products

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Aumitin Suppliers

TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
19892
Advantage
58
Aladdin Scientific
Tel
+1-+1(833)-552-7181
Email
sales@aladdinsci.com
Country
United States
ProdList
57511
Advantage
58

946293-78-3, AumitinRelated Search:


  • Aumitin
  • inhibit,Autophagy,Aumitin,Inhibitor
  • Benzamide, 2-chloro-N-[4-[[4-methyl-6-(phenylamino)-2-pyrimidinyl]amino]phenyl]-
  • 946293-78-3