ChemicalBook > CAS DataBase List > GNE-371

GNE-371

Product Name
GNE-371
CAS No.
1926986-36-8
Chemical Name
GNE-371
Synonyms
GNE-371;GNE 371,GNE371;GNE-371, 10 mM in DMSO;7H-Pyrrolo[2,3-c]pyridin-7-one, 6-(3-buten-1-yl)-1,6-dihydro-4-[1-methyl-6-(4-morpholinylcarbonyl)-1H-benzimidazol-4-yl]-
CBNumber
CB54844810
Molecular Formula
C24H25N5O3
Formula Weight
431.49
MOL File
1926986-36-8.mol
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GNE-371 Property

Boiling point:
737.1±70.0 °C(Predicted)
Density 
1.36±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
Soluble in DMSO
form 
Solid
pka
15.66±0.40(Predicted)
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

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GNE-371 Chemical Properties,Usage,Production

Uses

GNE-371 is a potent and selective chemical probe for the second bromodomains of human transcription-initiation-factor TFIID subunit 1 and transcription-initiation-factor TFIID subunit 1-like, with an IC50 of 10 nM for TAF1(2).

References

[1] Wang S, et al. GNE-371, a Potent and Selective Chemical Probe for the Second Bromodomains of Human Transcription-Initiation-Factor TFIID Subunit 1 and Transcription-Initiation-Factor TFIID Subunit 1-like. J Med Chem. 2018 Oct 25;61(20):9301-9315. DOI:10.1021/acs.jmedchem.8b01225

GNE-371 Preparation Products And Raw materials

Raw materials

Preparation Products

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GNE-371 Suppliers

Shanghai Beckham Medical Technology Co., Ltd
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13816613772
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QQ: 12922499
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huahero21@sina.com
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China
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Fan De(Beijing) Biotechnology Co., Ltd.
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15911056312
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liming@bio-fount.com
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China
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TargetMol Chemicals Inc.
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+1-781-999-5354; +17819995354
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marketing@targetmol.com
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United States
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HANGZHOU CLAP TECHNOLOGY CO.,LTD
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86-571-88216897,88216896 13588875226
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86-571-88216895
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sales@hzclap.com
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CHINA
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Suzhou youruike Chemical Pharmaceutical Technology Co., Ltd
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15317229551
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QQ:3607245178
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China
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Shanghai kadel chemical technology co., LTD
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021-4007787-550 400-7787-550
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2850202386@qq.com
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China
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TargetMol Chemicals Inc.
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4008200310
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marketing@tsbiochem.com
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China
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Shanghai Yifei Biotechnology Co. , Ltd.
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Nanjing Shizhou Biology Technology Co.,Ltd
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025-85560043 15850508050
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025-85563444
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RD International Technology Co., Limited
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1926986-36-8, GNE-371Related Search:


  • GNE-371
  • 7H-Pyrrolo[2,3-c]pyridin-7-one, 6-(3-buten-1-yl)-1,6-dihydro-4-[1-methyl-6-(4-morpholinylcarbonyl)-1H-benzimidazol-4-yl]-
  • GNE 371,GNE371
  • GNE-371, 10 mM in DMSO
  • 1926986-36-8