ChemicalBook > CAS DataBase List > GNE-371
GNE-371
- Product Name
- GNE-371
- CAS No.
- 1926986-36-8
- Chemical Name
- GNE-371
- Synonyms
- GNE-371;GNE 371,GNE371;GNE-371, 10 mM in DMSO;7H-Pyrrolo[2,3-c]pyridin-7-one, 6-(3-buten-1-yl)-1,6-dihydro-4-[1-methyl-6-(4-morpholinylcarbonyl)-1H-benzimidazol-4-yl]-
- CBNumber
- CB54844810
- Molecular Formula
- C24H25N5O3
- Formula Weight
- 431.49
- MOL File
- 1926986-36-8.mol
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GNE-371 Property
- Boiling point:
- 737.1±70.0 °C(Predicted)
- Density
- 1.36±0.1 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- Soluble in DMSO
- form
- Solid
- pka
- 15.66±0.40(Predicted)
- color
- White to off-white
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GNE-371 Chemical Properties,Usage,Production
Uses
GNE-371 is a potent and selective chemical probe for the second bromodomains of human transcription-initiation-factor TFIID subunit 1 and transcription-initiation-factor TFIID subunit 1-like, with an IC50 of 10 nM for TAF1(2).
References
[1] Wang S, et al. GNE-371, a Potent and Selective Chemical Probe for the Second Bromodomains of Human Transcription-Initiation-Factor TFIID Subunit 1 and Transcription-Initiation-Factor TFIID Subunit 1-like. J Med Chem. 2018 Oct 25;61(20):9301-9315. DOI:10.1021/acs.jmedchem.8b01225
GNE-371 Preparation Products And Raw materials
Raw materials
Preparation Products
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GNE-371 Suppliers
- Tel
- +1-781-999-5354; +17819995354
- marketing@targetmol.com
- Country
- United States
- ProdList
- 32435
- Advantage
- 58
- Tel
- tp@aladdinsci.com
- Country
- United States
- ProdList
- 52923
- Advantage
- 58