PXS-5153A

Product Name: PXS-5153A
CAS No.: 2125956-82-1
Chemical Name: PXS-5153A
Synonyms: PXS-5153A;LOX-IN-3 (PXS-5505);MAO,PXS-5153A,PXS 5153A,PXS5153A,inhibit,Inhibitor,Monoamine Oxidase;(Z)-3-(1-(4-Amino-2-fluorobut-2-en-1-yl)-2-methyl-1H-pyrrolo[3,2-b]pyridin-3-yl)-N,N-dimethylbenzenesulfonamide Dihydrochloride;3-{1-[(2Z)-4-Amino-2-fluorobut-2-en-1-yl]-2-methylpyrrolo[3,2-b]pyridin-3-yl}-N,N-dimethylbenzenesulfonamide dihydrochloride - [AC80868]
CBNumber: CB54845877
Molecular Formula: C20H24ClFN4O2S
Formula Weight: 438.95
MOL File: 2125956-82-1.mol

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PXS-5153A Property

storage temp.: Store at -20°C
solubility: Soluble in DMSO

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

DC Chemicals

Product number: DC12601
Product name: PXS-5153A
Purity: >98%
Packaging: 100mg
Price: $1100
Updated: 2021/12/16

DC Chemicals

Product number: DC12601
Product name: PXS-5153A
Purity: >98%
Packaging: 1g
Price: $4400
Updated: 2021/12/16

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PXS-5153A Chemical Properties,Usage,Production

Uses

A useful intermediate in the preparation of haloallylamine indole and azaindole derivatives which are lysyl oxidases inhibitors.

in vivo

As expected, rhLOXL2 dose-dependently induce oxidation of collagen with PXS-5153A dose-dependently impeding collagen oxidation. Therapeutic treatment of PXS-5153A substantially reduces immature crosslink formation compared with the CCl₄ treated animals. Mature crosslink formation is also reduced by PXS-5153A treatment. All groups with therapeutic treatment of PXS-5153A show a significant reduction in DHLNL formation compared to the CCl₄ treated animals. Treatment with PXS-5153A causes a significantly reduction in HYP compared to the CCl₄ group. In addition, the amount of fibrillar collagen is markedly augmented by disease as seen by the 2.2-fold increase in percentage coverage area by Picrosirius red staining, which is reduced by PXS-5153A^[1].

PXS-5153A Preparation Products And Raw materials

Raw materials

Preparation Products

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PXS-5153A Suppliers

China 18 United States 1 Global 19

ShangHai Caerulum Pharma Discovery Co., Ltd.

Tel: 18149758185
Email: sales-cpd@caerulumpharma.com
Country: China
ProdList: 3506
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Shanghai Vigor Biotechnology Co., Ltd.

Tel: 021-18017654 18017654809
Fax: 2271705492
Email: sales@vigorchem.cn
Country: China
ProdList: 958
Advantage: 58

Shanghai Changyu Medical Technology Co. Ltd.

Tel: +86-13301875428
Email: sales@changyuhe.com
Country: China
ProdList: 311
Advantage: 58

TargetMol Chemicals Inc.

Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
Country: United States
ProdList: 32435
Advantage: 58

Shanghai hongqu biomedical technology co. LTD

Tel: 88888888888
Email: hongquchem@qq.com
Country: China
ProdList: 5132
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Bide Pharmatech Ltd.

Tel: 400-1647117 13681763483
Email: product02@bidepharm.com
Country: China
ProdList: 59936
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hangzhoubaiyibiolog

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Fax: --
Email: sales@hzbybio.com
Country: China
ProdList: 22
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TargetMol Chemicals Inc.

Tel: 4008200310
Email: marketing@tsbiochem.com
Country: China
ProdList: 24961
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Shanghai Yifei Biotechnology Co. , Ltd.

Tel: 021-65675885 18964387627
Email: customer_service@efebio.com
Country: China
ProdList: 11973
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Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.

Tel: 025-025-66113011 18626450290
Email: cb5@aikonchem.com
Country: China
ProdList: 10358
Advantage: 58

2125956-82-1, PXS-5153ARelated Search:

PXS-5153A

(Z)-3-(1-(4-Amino-2-fluorobut-2-en-1-yl)-2-methyl-1H-pyrrolo[3,2-b]pyridin-3-yl)-N,N-dimethylbenzenesulfonamide Dihydrochloride

MAO,PXS-5153A,PXS 5153A,PXS5153A,inhibit,Inhibitor,Monoamine Oxidase

LOX-IN-3 (PXS-5505)

3-{1-[(2Z)-4-Amino-2-fluorobut-2-en-1-yl]-2-methylpyrrolo[3,2-b]pyridin-3-yl}-N,N-dimethylbenzenesulfonamide dihydrochloride - [AC80868]

2125956-82-1