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PXS-5153A

Product Name
PXS-5153A
CAS No.
2125956-82-1
Chemical Name
PXS-5153A
Synonyms
PXS-5153A;LOX-IN-3 (PXS-5505);MAO,PXS-5153A,PXS 5153A,PXS5153A,inhibit,Inhibitor,Monoamine Oxidase;(Z)-3-(1-(4-Amino-2-fluorobut-2-en-1-yl)-2-methyl-1H-pyrrolo[3,2-b]pyridin-3-yl)-N,N-dimethylbenzenesulfonamide Dihydrochloride;3-{1-[(2Z)-4-Amino-2-fluorobut-2-en-1-yl]-2-methylpyrrolo[3,2-b]pyridin-3-yl}-N,N-dimethylbenzenesulfonamide dihydrochloride - [AC80868]
CBNumber
CB54845877
Molecular Formula
C20H24ClFN4O2S
Formula Weight
438.95
MOL File
2125956-82-1.mol
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PXS-5153A Property

storage temp. 
Store at -20°C
solubility 
Soluble in DMSO
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

DC Chemicals
Product number
DC12601
Product name
PXS-5153A
Purity
>98%
Packaging
100mg
Price
$1100
Updated
2021/12/16
DC Chemicals
Product number
DC12601
Product name
PXS-5153A
Purity
>98%
Packaging
1g
Price
$4400
Updated
2021/12/16
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PXS-5153A Chemical Properties,Usage,Production

Uses

A useful intermediate in the preparation of haloallylamine indole and azaindole derivatives which are lysyl oxidases inhibitors.

in vivo

As expected, rhLOXL2 dose-dependently induce oxidation of collagen with PXS-5153A dose-dependently impeding collagen oxidation. Therapeutic treatment of PXS-5153A substantially reduces immature crosslink formation compared with the CCl4 treated animals. Mature crosslink formation is also reduced by PXS-5153A treatment. All groups with therapeutic treatment of PXS-5153A show a significant reduction in DHLNL formation compared to the CCl4 treated animals. Treatment with PXS-5153A causes a significantly reduction in HYP compared to the CCl4 group. In addition, the amount of fibrillar collagen is markedly augmented by disease as seen by the 2.2-fold increase in percentage coverage area by Picrosirius red staining, which is reduced by PXS-5153A[1].

PXS-5153A Preparation Products And Raw materials

Raw materials

Preparation Products

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PXS-5153A Suppliers

China 18 United States 1 Global 19
TargetMol Chemicals Inc.
Tel
+1-781-999-5354; +17819995354
Email
marketing@targetmol.com
Country
United States
ProdList
32435
Advantage
58

2125956-82-1, PXS-5153ARelated Search:


  • PXS-5153A
  • (Z)-3-(1-(4-Amino-2-fluorobut-2-en-1-yl)-2-methyl-1H-pyrrolo[3,2-b]pyridin-3-yl)-N,N-dimethylbenzenesulfonamide Dihydrochloride
  • MAO,PXS-5153A,PXS 5153A,PXS5153A,inhibit,Inhibitor,Monoamine Oxidase
  • LOX-IN-3 (PXS-5505)
  • 3-{1-[(2Z)-4-Amino-2-fluorobut-2-en-1-yl]-2-methylpyrrolo[3,2-b]pyridin-3-yl}-N,N-dimethylbenzenesulfonamide dihydrochloride - [AC80868]
  • 2125956-82-1