Indacaterol acetate
- Product Name
- Indacaterol acetate
- CAS No.
- 1000160-96-2
- Chemical Name
- Indacaterol acetate
- Synonyms
- Indacaterol Acetic;Indacaterol acetate;Indacaterol (Acetic Acid);(R)-5-(2-((5,6-diethyl-2,3-dihydro-1H-inden-2-yl)amino)-1-hydroxyethyl)-8-hydroxyquinolin-2(1H)-one acetate;acetic acid,5-[(1R)-2-[(5,6-diethyl-2,3-dihydro-1H-inden-2-yl)amino]-1-hydroxyethyl]-8-hydroxy-1H-quinolin-2-one
- CBNumber
- CB54848232
- Molecular Formula
- C26H32N2O5
- Formula Weight
- 452.55
- MOL File
- 1000160-96-2.mol
Indacaterol acetate Property
- InChIKey
- HZHXFIDENGBQFQ-MTFYFGCSNA-N
- SMILES
- C(=O)(O)C.[C@H](C1C=CC(O)=C2NC(=O)C=CC=12)(O)CNC1CC2=CC(CC)=C(CC)C=C2C1 |&1:4,r|
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
Indacaterol acetate Chemical Properties,Usage,Production
Uses
Indacaterol acetate is an orally active ultra-long-acting β2 adrenergic receptor (ADRB2) agonist. Indacaterol acetate inhibits NF-κB activity in a β-arrestin2-dependent manner, preventing further lung damage and improving lung function in COPD (chronic obstructive pulmonary disorder). Indacaterol acetate can also be used in cardiovascular disease research[1][2].
References
[1] Lee SU, et al. Indacaterol inhibits tumor cell invasiveness and MMP-9 expression by suppressing IKK/NF-κB activation. Mol Cells. 2014 Aug;37(8):585-91. DOI:10.14348/molcells.2014.0076
[2] Calzetta L, et al. Effects of the new ultra-long-acting β2-AR agonist indacaterol in chronic treatment alone or in combination with the β1-AR blocker metoprolol on cardiac remodelling. 2015. DOI:10.1097/FJC.0000000000000230
Indacaterol acetate Preparation Products And Raw materials
Raw materials
Preparation Products
Indacaterol acetate Suppliers
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View Lastest Price from Indacaterol acetate manufacturers
- Product
- Indacaterol Acetate 1000160-96-2
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 99% up
- Supply Ability
- 10TONS
- Release date
- 2025-11-11
- Product
- Indacaterol acetate 1000160-96-2
- Price
- US $30.00/g
- Min. Order
- 10g
- Purity
- 99%
- Supply Ability
- 10KG/M
- Release date
- 2023-08-11
- Product
- Indacaterol acetate 1000160-96-2
- Price
- US $70.00-700.00/kg
- Min. Order
- 10kg
- Purity
- 0.99
- Supply Ability
- 20tons
- Release date
- 2023-11-20