APN-C3-PEG4-alkyne

Product Name: APN-C3-PEG4-alkyne
CAS No.: 2183440-36-8
Chemical Name: APN-C3-PEG4-alkyne
Synonyms: APN-C3-PEG4-alkyne;9,12,15,18-Tetraoxa-5-azaheneicos-20-ynamide, N-[4-(2-cyanoethynyl)phenyl]-6-oxo-
CBNumber: CB54849406
Molecular Formula: C25H31N3O6
Formula Weight: 469.53
MOL File: 2183440-36-8.mol

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

BroadPharm

Product number: BP-23869
Product name: APN-C3-PEG4-alkyne
Purity: 98%
Packaging: 5mg
Price: $160
Updated: 2021/12/16

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APN-C3-PEG4-alkyne Chemical Properties,Usage,Production

Description

APN-C3-PEG4-alkyne is a heterobifunctional linker containing an APN moiety with exquisite chemoselectivity for cysteine and an alkyne group. The superior stability of APN-cysteine conjugates in aqueous media, human plasma, and living cells makes this new thiol-click reaction a promising methodology for applications in bioconjugation.

Uses

APN-C3-PEG4-alkyne is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. APN-C3-PEG4-alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

APN-C3-PEG4-alkyne Preparation Products And Raw materials

Raw materials

Preparation Products

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APN-C3-PEG4-alkyne Suppliers

China 14 United States 3 Global 17

Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd

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Xi'an Confluore Biological Technology Co., Ltd.

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Zhengzhou Acme Chemical Co., Ltd.

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Alfa Chemistry

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TargetMol Chemicals Inc.

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Shaanxi Xinyan Bomei Biotechnology Co., Ltd.

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Hangzhou Taorui Biotechnology Co., Ltd

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Beijing Jin Ming Biotechnology Co., Ltd.

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Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd

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Shanghai Easy CDMO Co.,Ltd

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View Lastest Price from APN-C3-PEG4-alkyne manufacturers

Xian confluore Biological Technology Co., Ltd.

Product: APN-C3-PEG4-alkyne 2183440-36-8
Price: US $0.00/mg
Min. Order: 25mg
Purity: >98.00%
Supply Ability: 25mg
Release date: 2024-03-25

2183440-36-8, APN-C3-PEG4-alkyneRelated Search:

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APN-C3-PEG4-alkyne

9,12,15,18-Tetraoxa-5-azaheneicos-20-ynamide, N-[4-(2-cyanoethynyl)phenyl]-6-oxo-

2183440-36-8