Methyltetrazine-PEG8-acid

Product Name: Methyltetrazine-PEG8-acid
CAS No.: 2183440-33-5
Chemical Name: Methyltetrazine-PEG8-acid
Synonyms: Methyltetrazine-PEG8-COOH;Methyltetrazine-PEG8-acid;1-[4-(6-methyl-1,2,4,5-tetrazin-3-yl)phenoxy]-3,6,9,12,15,18,21,24-octaoxaheptacosan-27-oic acid;Propanoic acid, 3-[[23-[4-(6-methyl-1,2,4,5-tetrazin-3-yl)phenoxy]-3,6,9,12,15,18,21-heptaoxatricos-1-yl]oxy]-;3-[2-[2-[2-[2-[2-[2-[2-[2-[4-(6-methyl-1,2,4,5-tetrazin-3-yl)phenoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid
CBNumber: CB54849613
Molecular Formula: C28H44N4O11
Formula Weight: 612.67
MOL File: 2183440-33-5.mol

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Methyltetrazine-PEG8-acid Property

solubility: Soluble in Water, DMSO, DCM, DMF
form: Solid
color: Purple to purplish red

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

BroadPharm

Product number: BP-23866
Product name: Methyltetrazine-PEG8-acid
Purity: 95%
Packaging: 50mg
Price: $430
Updated: 2021/12/16

BroadPharm

Product number: BP-23866
Product name: Methyltetrazine-PEG8-acid
Purity: 95%
Packaging: 100mg
Price: $680
Updated: 2021/12/16

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Methyltetrazine-PEG8-acid Chemical Properties,Usage,Production

Description

Methyltetrazine-PEG8-Acid is a click chemistry building block. In the presence of activators (e.g. EDC, or HATU), it can be used to conjugate with amine-containing molecule. PEG8 spacer increases the aqueous solubility of the compound. Methyltetrazine enable fast click chemistry with TCO ((trans-cycloctene) under mild condition

Uses

Methyltetrazine-PEG8-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

Methyltetrazine-PEG8-acid Preparation Products And Raw materials

Raw materials

Preparation Products

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Methyltetrazine-PEG8-acid Suppliers

China 15 United States 3 Global 18

Xi'an Confluore Biological Technology Co., Ltd.

Tel: +86-156-80926068 +86-15680926068
Email: 1924344760@qq.com
Country: China
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Alfa Chemistry

Tel: +1-5166625404;
Fax: 1-516-927-0118
Email: Info@alfa-chemistry.com
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TargetMol Chemicals Inc.

Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
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Shaanxi Xinyan Bomei Biotechnology Co., Ltd.

Tel: 13892832556
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Shanghai Haohong Pharmaceutical Co., Ltd.

Tel: 400-8210725 4008210725
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Beijing Jin Ming Biotechnology Co., Ltd.

Tel: 010-60605840 15801484223;
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Beijing Biocreative Technology Co., Ltd.

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Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd

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Shanghai Easy CDMO Co.,Ltd

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shanghai Yanfeng biochemical technology Co.,LTD

Tel: 17721070236 13611955358;
Email: yanfen2023@126.com
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View Lastest Price from Methyltetrazine-PEG8-acid manufacturers

Xian confluore Biological Technology Co., Ltd.

Product: Methyltetrazine-PEG8-COOH 2183440-33-5
Price: US $0.00/mg
Min. Order: 50mg
Purity: >99.00%
Supply Ability: 250mg
Release date: 2024-03-20

2183440-33-5, Methyltetrazine-PEG8-acidRelated Search:

Methyltetrazine-PEG8-acid

Propanoic acid, 3-[[23-[4-(6-methyl-1,2,4,5-tetrazin-3-yl)phenoxy]-3,6,9,12,15,18,21-heptaoxatricos-1-yl]oxy]-

3-[2-[2-[2-[2-[2-[2-[2-[2-[4-(6-methyl-1,2,4,5-tetrazin-3-yl)phenoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid

Methyltetrazine-PEG8-COOH

1-[4-(6-methyl-1,2,4,5-tetrazin-3-yl)phenoxy]-3,6,9,12,15,18,21,24-octaoxaheptacosan-27-oic acid

2183440-33-5

C28H44N4O11