ChemicalBook > CAS DataBase List > 3-(2-AMINO-ETHYL)-1H-INDOLE-5-CARBOXYLIC ACID AMIDE

3-(2-AMINO-ETHYL)-1H-INDOLE-5-CARBOXYLIC ACID AMIDE

Product Name
3-(2-AMINO-ETHYL)-1H-INDOLE-5-CARBOXYLIC ACID AMIDE
CAS No.
74885-09-9
Chemical Name
3-(2-AMINO-ETHYL)-1H-INDOLE-5-CARBOXYLIC ACID AMIDE
Synonyms
5-CT;5-CAT;5-carboxamidotryptamine;2-Carboxyamidotryptamine;5-Carboxamide tryptamine;5-Carboxyamidotryptamine;5-CARBOXAMINODOTRYPTAMINE;5-Carboxamidotryptamine, 5-CT;3-(2-Aminoethyl)-1H-indole-5-carboxamide;1H-Indole-5-carboxamide, 3-(2-aminoethyl)-
CBNumber
CB5487413
Molecular Formula
C11H13N3O
Formula Weight
203.24
MOL File
74885-09-9.mol
More
Less

3-(2-AMINO-ETHYL)-1H-INDOLE-5-CARBOXYLIC ACID AMIDE Property

Boiling point:
513.6±35.0 °C(Predicted)
Density 
1.293±0.06 g/cm3(Predicted)
storage temp. 
−20°C
solubility 
H2O: 10 mg/mL
form 
solid
pka
16.32±0.30(Predicted)
color 
white or off-white
Stability:
Hygroscopic
More
Less

Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
More
Less

Hazard and Precautionary Statements (GHS)

More
Less

N-Bromosuccinimide Price

American Custom Chemicals Corporation
Product number
CHM0075796
Product name
5-CARBOXAMIDOTRYPTAMINE
Purity
95.00%
Packaging
5MG
Price
$788.99
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0075796
Product name
5-CARBOXAMIDOTRYPTAMINE
Purity
95.00%
Packaging
25MG
Price
$1351
Updated
2021/12/16
More
Less

3-(2-AMINO-ETHYL)-1H-INDOLE-5-CARBOXYLIC ACID AMIDE Chemical Properties,Usage,Production

Uses

5-Carboxamidotryptamine maleate is an agonist of the 5-HT1 receptors.

Definition

ChEBI: 5-carboxamidotryptamine is a member of tryptamines.

in vivo

5-Carboxamidotryptamine (0.03-3 mg/kg i.p. and 0.125-5 μg i.c.v.) causes a dose-dependent reduction in rectal temperature of mice[3].
5-Carboxamidotryptamine (0.1-1 mg/kg; i.p.) reduces rectal temperature in wild type mice but not 5-HT7 receptor knockout mice[3].
5-Carboxamidotryptamine (0.0 1-1 μg/kg; i.v.) causes consistent, dose-related decreases in diastolic blood pressure and carotid arterial vascular resistance and increases in heart rate of cats. In contrast, 5-HT (1-100 μg/kg; i.v.) causes tachycardia but variable and complex effects on diastolic blood pressure and carotid arterial vascular resistance[5].
5-Carboxamidotryptamine does not cause bronchoconstriction in cats. In contrast, 5-HT causes dose-related bronchoconstriction[5].

Animal Model:Male Swiss Webster mice (20-25 g)[3]
Dosage:0.03-3 mg/kg (i.p.) and 0.125-5 μg (i.c.v.)
Administration:i.p. and i.c.v.
Result:Caused dose-dependent reduction in rectal temperature.
Animal Model:5-HT7 receptor knockout mice (background=50% 129SvEv/50% C57Bl/6J)[3]
Dosage:0.1-1 mg/kg
Administration:i.p. and i.c.v.
Result:Reduced rectal temperature in wild type but not 5-HT7 receptor knockout mice.

IC 50

5-HT1A Receptor; 5-HT1B Receptor; 5-HT1D Receptor; 5-HT5A Receptor; 5-HT7 Receptor

3-(2-AMINO-ETHYL)-1H-INDOLE-5-CARBOXYLIC ACID AMIDE Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

3-(2-AMINO-ETHYL)-1H-INDOLE-5-CARBOXYLIC ACID AMIDE Suppliers

China 12 Germany 2 India 1 Switzerland 1 United Kingdom 4 United States 3 Global 23
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15838
Advantage
69
Shanghai Lollane Biological Technology Co.,Ltd.
Tel
021-52996696，15000506266 15000506266
Fax
+86-21-52996696
Country
China
ProdList
4757
Advantage
55
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131957
Advantage
58
Suzhou Chenrui Biotechnology Co. LTD
Tel
17625585511
Fax
qq：1580084073
Email
1580084073@qq.com
Country
China
ProdList
960
Advantage
58
Energy Chemical
Tel
021-58432009 400-005-6266
Fax
021-58436166
Email
marketing@energy-chemical.com
Country
China
ProdList
44918
Advantage
58
Aikon International Limited
Tel
025-58859352 18651614124
Email
2881516338@qq.com
Country
China
ProdList
10000
Advantage
58
Biosynth Biological Technology (Suzhou) Co Ltd
Tel
51288865780
Email
sales@biosynth.com
Country
China
ProdList
6051
Advantage
58
Santa Cruz Biotechnology Inc
Tel
021-60936350
Email
scbt@scbt.com
Country
China
ProdList
6594
Advantage
58
DAYANG CHEM (HANGZHOU) CO.,LTD
Tel
+86-88938639 +86-17705817739
Email
info@dycnchem.com
Country
China
ProdList
53899
Advantage
58
Hangzhou MolCore BioPharmatech Co.,Ltd.
Tel
+86-057181025280; +8617767106207
Fax
0571-85806285
Email
sales@molcore.com
Country
China
ProdList
49734
Advantage
58
Absin Bioscience Inc.
Tel
--
Fax
--
Email
chenjw@absin.cn
Country
CHINA
ProdList
6208
Advantage
58
Beijing Seajet Scientific Inc
Tel
--
Fax
--
Email
info@seajetsci.com
Country
China
ProdList
377
Advantage
70

74885-09-9, 3-(2-AMINO-ETHYL)-1H-INDOLE-5-CARBOXYLIC ACID AMIDERelated Search:

Indole-5-carboxylic acid 5-CARBOXAMIDO[3H]TRYPTAMINE, TRIFLUOROACETATE 5-carboxamidotryptamine maleate salt 5-CARBOXAMIDOTRYPTAMINE, [1,2-3H]- 6-(1,3-DIOXO-1,3-DIHYDRO-ISOINDOL-2-YL)-6,7,8,9-TETRAHYDRO-5H-CARBAZOLE-3-CARBOXYLIC ACID AMIDE 6-AMINO-6,7,8,9-TETRAHYDRO-5H-CARBAZOLE-3-CARBOXYLIC ACID AMIDE 3-(2-AMINO-ETHYL)-1H-INDOLE-5-CARBOXYLIC ACID AMIDE FROVATRIPTAN N,N-DIPROPYL-5-CARBOXAMIDOTRYPTAMINE MALEATE

  • 3-(2-AMINO-ETHYL)-1H-INDOLE-5-CARBOXYLIC ACID AMIDE
  • 5-CARBOXAMINODOTRYPTAMINE
  • 5-CT
  • 5-CARBOXAMIDOTRYPTAMINE HEMIETHANOLATE MALEATE SALT
  • 5-carboxamidotryptamine
  • 2-Carboxyamidotryptamine
  • 3-(2-Aminoethyl)-1H-indole-5-carboxamide
  • 5-Carboxyamidotryptamine
  • 5-CAT
  • 1H-Indole-5-carboxamide, 3-(2-aminoethyl)-
  • 5-Carboxamide tryptamine
  • 5-Carboxamidotryptamine, 5-CT
  • 74885-09-9
  • pharmacetical
  • Serotonin receptor