15-(2-Pyridyldithio)-4,7,10,13-tetraoxapentadecanoic acid, N-hydroxysuccinimide ester

Product Name: 15-(2-Pyridyldithio)-4,7,10,13-tetraoxapentadecanoic acid, N-hydroxysuccinimide ester
CAS No.: 1305053-43-3
Chemical Name: 15-(2-Pyridyldithio)-4,7,10,13-tetraoxapentadecanoic acid, N-hydroxysuccinimide ester
Synonyms: Pyridin-2-yldisulfanyl-PEG4-NHS;2,5-dioxo-1-pyrrolidinyl 15-(2-Pyridinyldithio)-4,7,10,13-tetraoxapentadecanoate;15-(2-Pyridyldithio)-4,7,10,13-tetraoxapentadecanoic acid, N-hydroxysuccinimide ester;2,5-dioxopyrrolidin-1-yl 1-(pyridin-2-yldisulfaneyl)-3,6,9,12-tetraoxapentadecan-15-oate;4,7,10,13-Tetraoxapentadecanoic acid, 15-(2-pyridinyldithio)-, 2,5-dioxo-1-pyrrolidinyl ester;(2,5-dioxopyrrolidin-1-yl) 3-[2-[2-[2-[2-(2-pyridyldisulfanyl)ethoxy]ethoxy]ethoxy]ethoxy]propanoate
CBNumber: CB54903007
Molecular Formula: C20H28N2O8S2
Formula Weight: 488.57
MOL File: 1305053-43-3.mol

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15-(2-Pyridyldithio)-4,7,10,13-tetraoxapentadecanoic acid, N-hydroxysuccinimide ester Property

Boiling point:: 605.9±65.0 °C(Predicted)
Density: 1.34±0.1 g/cm3(Predicted)
storage temp.: Storage temp. -20°C
form: Viscous Liquid
pka: 1.81±0.12(Predicted)
color: Colorless to light yellow

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC

Product number: T890188
Product name: 2,5-dioxo-1-pyrrolidinyl15-(2-Pyridinyldithio)-4,7,10,13-tetraoxapentadecanoate
Packaging: 2mg
Price: $65
Updated: 2021/12/16

ChemScene

Product number: CS-0104976
Product name: PEG4-SPDP
Packaging: 100mg
Price: $850
Updated: 2021/12/16

SynChem

Product number: SC-27112
Product name: Pyridin-2-yldisulfanyl-PEG4-NHS
Purity: 90+%
Packaging: 1g
Price: $1950
Updated: 2021/12/16

Alichem

Product number: 1305053433
Product name: 15-(2-pyridyldithio)-4,7,10,13-tetraoxapentadecanoicacidN-hydroxysuccinimideester
Packaging: 1g
Price: $2279.88
Updated: 2021/12/16

SynChem

Product number: SC-27112
Product name: Pyridin-2-yldisulfanyl-PEG4-NHS
Purity: 90+%
Packaging: 250mg
Price: $695
Updated: 2021/12/16

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15-(2-Pyridyldithio)-4,7,10,13-tetraoxapentadecanoic acid, N-hydroxysuccinimide ester Chemical Properties,Usage,Production

Uses

PEG4-SPDP is a cleavable ADC linker used for the antibody-drug conjugates (ADCs).

IC 50

Disulfide Cleavable Linker; Cleavable Linker

References

[1] Zhao RY, et al. Synthesis and evaluation of hydrophilic linkers for antibody-maytansinoid conjugates. J Med Chem. 2011 May 26;54(10):3606-23. DOI:10.1021/jm2002958

15-(2-Pyridyldithio)-4,7,10,13-tetraoxapentadecanoic acid, N-hydroxysuccinimide ester Preparation Products And Raw materials

Raw materials

Preparation Products

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15-(2-Pyridyldithio)-4,7,10,13-tetraoxapentadecanoic acid, N-hydroxysuccinimide ester Suppliers

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Shanghai EFE Biological Technology Co., Ltd.

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View Lastest Price from 15-(2-Pyridyldithio)-4,7,10,13-tetraoxapentadecanoic acid, N-hydroxysuccinimide ester manufacturers

Xian confluore Biological Technology Co., Ltd.

Product: PEG4-SPDP 1305053-43-3
Price: US $0.00/mg
Min. Order: 250mg
Purity: >95.00%
Supply Ability: 250mg
Release date: 2024-03-27

1305053-43-3, 15-(2-Pyridyldithio)-4,7,10,13-tetraoxapentadecanoic acid, N-hydroxysuccinimide esterRelated Search:

15-(2-Pyridyldithio)-4,7,10,13-tetraoxapentadecanoic acid, N-hydroxysuccinimide ester

Pyridin-2-yldisulfanyl-PEG4-NHS

2,5-dioxopyrrolidin-1-yl 1-(pyridin-2-yldisulfaneyl)-3,6,9,12-tetraoxapentadecan-15-oate

2,5-dioxo-1-pyrrolidinyl 15-(2-Pyridinyldithio)-4,7,10,13-tetraoxapentadecanoate

(2,5-dioxopyrrolidin-1-yl) 3-[2-[2-[2-[2-(2-pyridyldisulfanyl)ethoxy]ethoxy]ethoxy]ethoxy]propanoate

4,7,10,13-Tetraoxapentadecanoic acid, 15-(2-pyridinyldithio)-, 2,5-dioxo-1-pyrrolidinyl ester

1305053-43-3

C20H28N2O8S2