15-(2-Pyridyldithio)-4,7,10,13-tetraoxapentadecanoic acid, N-hydroxysuccinimide ester

Product Name: 15-(2-Pyridyldithio)-4,7,10,13-tetraoxapentadecanoic acid, N-hydroxysuccinimide ester
CAS No.: 1305053-43-3
Chemical Name: 15-(2-Pyridyldithio)-4,7,10,13-tetraoxapentadecanoic acid, N-hydroxysuccinimide ester
Synonyms: Pyridin-2-yldisulfanyl-PEG4-NHS;2,5-dioxo-1-pyrrolidinyl 15-(2-Pyridinyldithio)-4,7,10,13-tetraoxapentadecanoate;15-(2-Pyridyldithio)-4,7,10,13-tetraoxapentadecanoic acid, N-hydroxysuccinimide ester;2,5-dioxopyrrolidin-1-yl 1-(pyridin-2-yldisulfaneyl)-3,6,9,12-tetraoxapentadecan-15-oate;4,7,10,13-Tetraoxapentadecanoic acid, 15-(2-pyridinyldithio)-, 2,5-dioxo-1-pyrrolidinyl ester;(2,5-dioxopyrrolidin-1-yl) 3-[2-[2-[2-[2-(2-pyridyldisulfanyl)ethoxy]ethoxy]ethoxy]ethoxy]propanoate
CBNumber: CB54903007
Molecular Formula: C20H28N2O8S2
Formula Weight: 488.57
MOL File: 1305053-43-3.mol

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15-(2-Pyridyldithio)-4,7,10,13-tetraoxapentadecanoic acid, N-hydroxysuccinimide ester Property

Boiling point:: 605.9±65.0 °C(Predicted)
Density: 1.34±0.1 g/cm3(Predicted)
storage temp.: Storage temp. -20°C
form: Viscous Liquid
pka: 1.81±0.12(Predicted)
color: Colorless to light yellow

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC

Product number: T890188
Product name: 2,5-dioxo-1-pyrrolidinyl15-(2-Pyridinyldithio)-4,7,10,13-tetraoxapentadecanoate
Packaging: 2mg
Price: $65
Updated: 2021/12/16

ChemScene

Product number: CS-0104976
Product name: PEG4-SPDP
Packaging: 100mg
Price: $850
Updated: 2021/12/16

SynChem

Product number: SC-27112
Product name: Pyridin-2-yldisulfanyl-PEG4-NHS
Purity: 90+%
Packaging: 250mg
Price: $695
Updated: 2021/12/16

SynChem

Product number: SC-27112
Product name: Pyridin-2-yldisulfanyl-PEG4-NHS
Purity: 90+%
Packaging: 1g
Price: $1950
Updated: 2021/12/16

Alichem

Product number: 1305053433
Product name: 15-(2-pyridyldithio)-4,7,10,13-tetraoxapentadecanoicacidN-hydroxysuccinimideester
Packaging: 1g
Price: $2279.88
Updated: 2021/12/16

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15-(2-Pyridyldithio)-4,7,10,13-tetraoxapentadecanoic acid, N-hydroxysuccinimide ester Chemical Properties,Usage,Production

Uses

PEG4-SPDP is a cleavable ADC linker used for the antibody-drug conjugates (ADCs).

IC 50

Disulfide Cleavable Linker; Cleavable Linker

References

[1] Zhao RY, et al. Synthesis and evaluation of hydrophilic linkers for antibody-maytansinoid conjugates. J Med Chem. 2011 May 26;54(10):3606-23. DOI:10.1021/jm2002958

15-(2-Pyridyldithio)-4,7,10,13-tetraoxapentadecanoic acid, N-hydroxysuccinimide ester Preparation Products And Raw materials

Raw materials

Preparation Products

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15-(2-Pyridyldithio)-4,7,10,13-tetraoxapentadecanoic acid, N-hydroxysuccinimide ester Suppliers

China 26 United States 5 Global 31

Shanghai EFE Biological Technology Co., Ltd.

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View Lastest Price from 15-(2-Pyridyldithio)-4,7,10,13-tetraoxapentadecanoic acid, N-hydroxysuccinimide ester manufacturers

Xian confluore Biological Technology Co., Ltd.

Product: PEG4-SPDP 1305053-43-3
Price: US $0.00/mg
Min. Order: 250mg
Purity: >95.00%
Supply Ability: 250mg
Release date: 2024-03-27

1305053-43-3, 15-(2-Pyridyldithio)-4,7,10,13-tetraoxapentadecanoic acid, N-hydroxysuccinimide esterRelated Search:

15-(2-Pyridyldithio)-4,7,10,13-tetraoxapentadecanoic acid, N-hydroxysuccinimide ester

Pyridin-2-yldisulfanyl-PEG4-NHS

2,5-dioxopyrrolidin-1-yl 1-(pyridin-2-yldisulfaneyl)-3,6,9,12-tetraoxapentadecan-15-oate

2,5-dioxo-1-pyrrolidinyl 15-(2-Pyridinyldithio)-4,7,10,13-tetraoxapentadecanoate

(2,5-dioxopyrrolidin-1-yl) 3-[2-[2-[2-[2-(2-pyridyldisulfanyl)ethoxy]ethoxy]ethoxy]ethoxy]propanoate

4,7,10,13-Tetraoxapentadecanoic acid, 15-(2-pyridinyldithio)-, 2,5-dioxo-1-pyrrolidinyl ester

1305053-43-3

C20H28N2O8S2