5-Aminouridine

Product Name: 5-Aminouridine
CAS No.: 2149-76-0
Chemical Name: 5-Aminouridine
Synonyms: 5-aminouridine;Uridine, 5-amino-;5-Aminouridine Hcl;5-AminouridineHClsalt;Uridine, 5-amino-(6CI,7CI,8CI,9CI);5-amino-1-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione;5-azanyl-1-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione;5-amino-1-(3,4-dihydroxy-5-methylol-tetrahydrofuran-2-yl)pyrimidine-2,4-quinone;5-Amino-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione
CBNumber: CB5496873
Molecular Formula: C9H13N3O6
Formula Weight: 259.22
MOL File: 2149-76-0.mol

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5-Aminouridine Property

Melting point:: 214-216 °C
Density: 1.712±0.06 g/cm3(Predicted)
storage temp.: −20°C
pka: 9.31±0.10(Predicted)
InChI: InChI=1S/C9H13N3O6/c10-3-1-12(9(17)11-7(3)16)8-6(15)5(14)4(2-13)18-8/h1,4-6,8,13-15H,2,10H2,(H,11,16,17)/t4-,5-,6-,8-/m1/s1
InChIKey: YBTWWWIJBCCYNR-UAKXSSHOSA-N
SMILES: OC[C@H]1O[C@@H](N2C=C(N)C(=O)NC2=O)[C@H](O)[C@@H]1O

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Safety

WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Crysdot

Product number: CD70001702
Product name: 5-Amino-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione
Purity: 95+%
Packaging: 250mg
Price: $300
Updated: 2021/12/16

Chemenu

Product number: CM322243
Product name: 5-Amino-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione
Purity: 95%
Packaging: 1g
Price: $701
Updated: 2021/12/16

Crysdot

Product number: CD70001702
Product name: 5-Amino-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione
Purity: 95+%
Packaging: 1g
Price: $750
Updated: 2021/12/16

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5-Aminouridine Chemical Properties,Usage,Production

Description

5-Aminouridine can modify nucleobases and can be incorporated into the target DNA. 5-Aminouridine exhibits a wide range of biological activity and it inhibits the growth of tumors, fungi and viruses.

in vitro

This modified nucleobase, 5-Aminouridine, must exhibit a low enough potential to be oxidized by Os(bpy)3³⁺. These modified nucleobases can be inserted into the target DNA by direct synthesis using modified phosphoramidites

in vivo

5-Aminouridine inhibits the incorporation of carbamyl aspartate into pyrimidines of both RNA and DNA in rat lived and [32P]phosphate into phospholipids and RNA nucleotides of rat liver slices and hepatoma. 5-Aminouridine was found to be incorporated into the RNA of Ehrlich ascites cells, and 5-aminouridine monophosphate was shown to be a strong inhibitor of orotidine 5'-phosphate decarboxylase[1].

References

[1] David A. Smith, Donald W. Visser, P. Roy-Burman. “Studies on 5-aminouridine.” Biochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis 119 2 (1966): Pages 221-228.

5-Aminouridine Preparation Products And Raw materials

Raw materials

Preparation Products

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5-Aminouridine Suppliers

Canada 1 China 22 Germany 1 Russia 1 Switzerland 1 United States 5 Global 31

T&W GROUP

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Aikon International Limited

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Zhengzhou Granlen Sciences, ltd.

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NewCan Biotech Limited

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BOC Sciences

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TargetMol Chemicals Inc.

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2149-76-0, 5-Aminouridine Related Search:

Uridine, 5-amino-(6CI,7CI,8CI,9CI)

5-aminouridine

5-AminouridineHClsalt

5-amino-1-(3,4-dihydroxy-5-methylol-tetrahydrofuran-2-yl)pyrimidine-2,4-quinone

5-amino-1-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione

5-azanyl-1-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione

5-Aminouridine Hcl

5-Amino-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione

Uridine, 5-amino-

2149-76-0

C9H14ClN3O6

C9H13N3O6HCl