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5-Aminouridine

Product Name
5-Aminouridine
CAS No.
2149-76-0
Chemical Name
5-Aminouridine
Synonyms
5-aminouridine;5-Amino-uridin;Uridine, 5-amino-;5-Aminouridine Hcl;5-AminouridineHClsalt;Uridine, 5-amino-(6CI,7CI,8CI,9CI);5-amino-1-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione;5-azanyl-1-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione;5-amino-1-(3,4-dihydroxy-5-methylol-tetrahydrofuran-2-yl)pyrimidine-2,4-quinone;5-Amino-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione
CBNumber
CB5496873
Molecular Formula
C9H13N3O6
Formula Weight
259.22
MOL File
2149-76-0.mol
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5-Aminouridine Property

Melting point:
214-216 °C
Density 
1.712±0.06 g/cm3(Predicted)
storage temp. 
−20°C
pka
9.31±0.10(Predicted)
InChI
InChI=1S/C9H13N3O6/c10-3-1-12(9(17)11-7(3)16)8-6(15)5(14)4(2-13)18-8/h1,4-6,8,13-15H,2,10H2,(H,11,16,17)/t4-,5-,6-,8-/m1/s1
InChIKey
YBTWWWIJBCCYNR-UAKXSSHOSA-N
SMILES
OC[C@H]1O[C@@H](N2C=C(N)C(=O)NC2=O)[C@H](O)[C@@H]1O
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Crysdot
Product number
CD70001702
Product name
5-Amino-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione
Purity
95+%
Packaging
250mg
Price
$300
Updated
2021/12/16
Chemenu
Product number
CM322243
Product name
5-Amino-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione
Purity
95%
Packaging
1g
Price
$701
Updated
2021/12/16
Crysdot
Product number
CD70001702
Product name
5-Amino-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione
Purity
95+%
Packaging
1g
Price
$750
Updated
2021/12/16
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5-Aminouridine Chemical Properties,Usage,Production

Description

5-Aminouridine can modify nucleobases and can be incorporated into the target DNA. 5-Aminouridine exhibits a wide range of biological activity and it inhibits the growth of tumors, fungi and viruses.

in vitro

This modified nucleobase, 5-Aminouridine, must exhibit a low enough potential to be oxidized by Os(bpy)33+. These modified nucleobases can be inserted into the target DNA by direct synthesis using modified phosphoramidites

in vivo

5-Aminouridine inhibits the incorporation of carbamyl aspartate into pyrimidines of both RNA and DNA in rat lived and [32P]phosphate into phospholipids and RNA nucleotides of rat liver slices and hepatoma. 5-Aminouridine was found to be incorporated into the RNA of Ehrlich ascites cells, and 5-aminouridine monophosphate was shown to be a strong inhibitor of orotidine 5'-phosphate decarboxylase[1].

References

[1] David A. Smith, Donald W. Visser, P. Roy-Burman. “Studies on 5-aminouridine.” Biochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis 119 2 (1966): Pages 221-228.

5-Aminouridine Preparation Products And Raw materials

Raw materials

Preparation Products

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5-Aminouridine Suppliers

TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
32161
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58
BOC Sciences
Tel
16314854226; +16314854226
Email
inquiry@bocsci.com
Country
United States
ProdList
19741
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58
TargetMol Chemicals Inc.
Tel
Email
support@targetmol.com
Country
United States
ProdList
38631
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58
MedChemExpress
Tel
--
Fax
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Email
sales@medchemexpress.com
Country
United States
ProdList
6398
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58
Riedel-de Haen AG
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--
Fax
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Country
United States
ProdList
6773
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87
HONEST JOY HOLDINGS LIMITED
Tel
--
Fax
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Email
sales@honestjoy.cn
Country
United States
ProdList
6675
Advantage
54

2149-76-0, 5-Aminouridine Related Search:


  • Uridine, 5-amino-(6CI,7CI,8CI,9CI)
  • 5-aminouridine
  • 5-AminouridineHClsalt
  • 5-amino-1-(3,4-dihydroxy-5-methylol-tetrahydrofuran-2-yl)pyrimidine-2,4-quinone
  • 5-amino-1-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione
  • 5-azanyl-1-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione
  • 5-Aminouridine Hcl
  • 5-Amino-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione
  • Uridine, 5-amino-
  • 5-Amino-uridin
  • 2149-76-0
  • C9H14ClN3O6
  • C9H13N3O6HCl