QUINELORANE 2HCL
- Product Name
- QUINELORANE 2HCL
- CAS No.
- 97548-97-5
- Chemical Name
- QUINELORANE 2HCL
- Synonyms
- QUINELORANE 2HCL;Quinelorane hydrochloride;QUINELORANE DIHYDROCHLORIDE (LY-163,502) D2 DOPAMINE RECEPTOR;(5aR,9aR)-5,5a,6,7,8,9,9a,10-Octahydro-6-propylpyrido[2,3-g]quinazolin-2-aminedihydrochloride;LY-163,502, (5aR-trans)-5,5a,6,7,8,9,9a,10-Octahydro-6-propylpyrido[2,3-g]quinazolin-2-amine dihydrochloride
- CBNumber
- CB5497092
- Molecular Formula
- C14H23ClN4
- Formula Weight
- 282.82
- MOL File
- 97548-97-5.mol
QUINELORANE 2HCL Property
- storage temp.
- Desiccate at RT
- solubility
- H2O: >10mg/mL
- form
- Powder
- color
- white
- Water Solubility
- Soluble to 25 mM in water
N-Bromosuccinimide Price
- Product number
- 1519
- Product name
- Quineloranehydrochloride
- Purity
- ≥99%(HPLC)
- Packaging
- 10
- Price
- $255
- Updated
- 2021/12/16
- Product number
- Q670405
- Product name
- QuineloraneDihydrochloride
- Packaging
- 10mg
- Price
- $235
- Updated
- 2021/12/16
- Product number
- B6775
- Product name
- Quineloranehydrochloride
- Packaging
- 10mg
- Price
- $377
- Updated
- 2021/12/16
- Product number
- API0007821
- Product name
- QUINELORANE DIHYDROCHLORIDE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $475
- Updated
- 2021/12/16
- Product number
- API0007821
- Product name
- QUINELORANE DIHYDROCHLORIDE
- Purity
- 95.00%
- Packaging
- 10MG
- Price
- $520
- Updated
- 2021/12/16
QUINELORANE 2HCL Chemical Properties,Usage,Production
Uses
Antihypertensive; antiparkinsonian.
Uses
Quinelorane Dihydrochloride is a D2DR agonist.
Biological Activity
Dopamine D 2 and D 3 receptor agonist; K i values are 5.7 and 3.4 nM respectively.
in vivo
Quinelorane dihydrochloride (LY163502; 0.003, 0.01 mg/kg; s.c.) reduces GABA efflux, with significant effects with 0.01 but not 0.003 mg/kg in male Wistar rats (300 g)[1].
Quinelorane dihydrochloride (0.032, 0.32, 3.2, 5.6 mg/kg; IP) significantly and dose-dependently increases locomotor activity in the Sprague Dawley rats. There was no main effect of sex and sex interaction[1].
Quinelorane dihydrochloride significantly decreases activity in the male and female inbred FVB/NJ, BALB/cJ, BALB/cByJ, C57BL/6J, Swiss Webster, A/J, DBA/2J, 129S1/SvImJ, and 129S6/SvEvTac mice[1].
IC 50
D2 Receptor; D3 Receptor
storage
Desiccate at RT
QUINELORANE 2HCL Preparation Products And Raw materials
Raw materials
Preparation Products
QUINELORANE 2HCL Suppliers
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