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SM-19712

Product Name
SM-19712
CAS No.
194542-56-8
Chemical Name
SM-19712
Synonyms
SM19712 sodium;SM-19712 hydrate;4-chloro-n-[[(4-cyano-3-methyl-1-phenyl-1h-pyrazol-5-yl)amino]carbonyl]benzenesulfonamide sodium salt;4-Chloro-N-[[(4-cyano-3-methyl-1-phenyl-1H-pyrazol-5-yl)amino]carbonyl]benzenesulfonamide sodium salt hydrate
CBNumber
CB5497476
Molecular Formula
C18H15ClN5NaO3S
Formula Weight
439.85
MOL File
194542-56-8.mol
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SM-19712 Property

storage temp. 
2-8°C
solubility 
H2O: ~28 mg/mL
form 
solid
color 
off-white
InChI
1S/C12H10ClN5O3S.Na.H2O/c1-7-10(6-14)11(17-16-7)15-12(19)18-22(20,21)9-4-2-8(13)3-5-9;;/h2-5H,1H3,(H3,15,16,17,18,19);;1H2/q;+1;/p-1
InChIKey
HLHPDQXMLDUDQV-UHFFFAOYSA-M
SMILES
ClC1=CC=C(S(N(C(NC2=C(C#N)C(C)=NN2C3=CC=CC=C3)=O)[Na])(=O)=O)C=C1
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
Storage Class
11 - Combustible Solids
Hazard Classifications
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
S3445
Product name
SM-19712 hydrate
Purity
≥98% (HPLC)
Packaging
5mg
Price
$259
Updated
2026/03/19
Sigma-Aldrich
Product number
S3445
Product name
SM-19712 hydrate
Purity
≥98% (HPLC)
Packaging
25mg
Price
$958
Updated
2026/03/19
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SM-19712 Chemical Properties,Usage,Production

Uses

SM-19712 hydrate was used in studies to determine the effectiveness of ECE inhibition as a treatment option for Alzheimerμs disease.

Biological Activity

SM-19712 a sulfonylureid-pyrazole derivative is a potent and selective inhibitor of endothelin converting enzyme (ECE). It attenuates the effects of ischemic acute renal failure and reduces the inflammation, tissue injury and vasoconstriction induced by dextran sodium sulfate in mouse colon.', 'Nonpeptide, potent and selective endothelin converting enzyme inhibitor.

SM-19712 Preparation Products And Raw materials

Raw materials

Preparation Products

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SM-19712 Suppliers

China 5 Switzerland 1 United States 3 Global 9
Guangzhou Isun Pharmaceutical Co., Ltd
Tel
020-39119399 18927568969
Fax
020-39119999
Email
isunpharm@qq.com
Country
China
ProdList
4769
Advantage
55
TargetMol Chemicals Inc.
Tel
+1-781-999-5354; +17819995354
Email
marketing@targetmol.com
Country
United States
ProdList
32467
Advantage
58
TargetMol Chemicals Inc.
Tel
15002134094
Email
marketing@targetmol.cn
Country
China
ProdList
29430
Advantage
58
Merck KGaA
Tel
21-20338288
Email
ordercn@merckgroup.com
Country
China
ProdList
6038
Advantage
58
Aladdin Scientific
Tel
Email
tp@aladdinsci.com
Country
United States
ProdList
52923
Advantage
58

194542-56-8, SM-19712Related Search:


  • SM-19712 hydrate
  • 4-Chloro-N-[[(4-cyano-3-methyl-1-phenyl-1H-pyrazol-5-yl)amino]carbonyl]benzenesulfonamide sodium salt hydrate
  • 4-chloro-n-[[(4-cyano-3-methyl-1-phenyl-1h-pyrazol-5-yl)amino]carbonyl]benzenesulfonamide sodium salt
  • SM19712 sodium
  • 194542-56-8
  • C18H13ClN5NaO3S