5-(2-BENZOTHIAZOLYL)-3-ETHYL-2-(-(METHY

Product Name: 5-(2-BENZOTHIAZOLYL)-3-ETHYL-2-(-(METHY
CAS No.: 681281-88-9
Chemical Name: 5-(2-BENZOTHIAZOLYL)-3-ETHYL-2-(-(METHY
Synonyms: 5-(2-BENZOTHIAZOLYL)-3-ETHYL-2-(-(METHY;Akt Inhibitor IV - CAS 681281-88-9 - Calbiochem;6-(2-Benzothiazolyl)-1-ethyl-2-[2-(methylphenylamino)ethenyl]-3-phenyl-1H-benzimidazolium iodide;6-benzothiazol-2-yl-1-ethyl-2-[2-(methyl-phenyl-amino)-vinyl]-3-phenyl-3H-benzoimidazol-1-ium iodide;5-(Benzo[d]thiazol-2-yl)-3-ethyl-2-(2-(methyl(phenyl)amino)vinyl)-1-phenyl-1H-benzo[d]imidazol-3-ium iodide;(E)-5-(benzo[d]thiazol-2-yl)-3-ethyl-2-(2-(methyl(phenyl)amino)vinyl)-1-phenyl-1H-benzo[d]imidazol-3-ium iodide
CBNumber: CB5497911
Molecular Formula: C31H27N4S.I
Formula Weight: 614.548
MOL File: 681281-88-9.mol

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5-(2-BENZOTHIAZOLYL)-3-ETHYL-2-(-(METHY Property

storage temp.: 2-8°C
solubility: DMSO: ≥10 mg/mL
form: solid
color: orange
InChIKey: NAYRELMNTQSBIN-UHFFFAOYSA-M

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36
WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 124011
Product name: Akt Inhibitor IV
Packaging: 1mg
Price: $172
Updated: 2024/03/01

Sigma-Aldrich

Product number: 124011
Product name: Akt Inhibitor IV
Packaging: 5mg
Price: $619
Updated: 2024/03/01

Cayman Chemical

Product number: 15569
Product name: Akt Inhibitor IV
Purity: ≥95%
Packaging: 1mg
Price: $40
Updated: 2024/03/01

Cayman Chemical

Product number: 15569
Product name: Akt Inhibitor IV
Purity: ≥95%
Packaging: 5mg
Price: $177
Updated: 2024/03/01

Sigma-Aldrich

Product number: B2311
Product name: 5-(2-Benzothiazolyl)-3-ethyl-2-[2-(methylphenylamino)ethenyl]-1-phenyl-1H-benzimidazolium iodide
Purity: ≥98% (HPLC)
Packaging: 5mg
Price: $205
Updated: 2024/03/01

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5-(2-BENZOTHIAZOLYL)-3-ETHYL-2-(-(METHY Chemical Properties,Usage,Production

Uses

Akt Inhibitor IV is an Inhibitor of Akt protein kinase

Biological Activity

akt inhibitor iv is an inhibitor of akt activation that inhibits akt-mediated nuclear export of forkhead box class o transcription factor 1a (foxo1a; ic50 = 625 nm) and reduces phosphorylation of akt at ser473 and thr308 in a dose-dependent manner. akt inhibitor iv inhibits replication of parainfluenza virus 5 (piv5) in hela cells (ic50 = 520 nm). it also reduces the growth of cancer cells (ic50 = 0.3 μm for both jurkat and hela cells) via a reduction in mitochondrial polarization and increased production of reactive oxygen species (ros).

5-(2-BENZOTHIAZOLYL)-3-ETHYL-2-(-(METHY Preparation Products And Raw materials

Raw materials

Preparation Products

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5-(2-BENZOTHIAZOLYL)-3-ETHYL-2-(-(METHY Suppliers

China 26 Switzerland 1 United Kingdom 1 United States 7 Global 35

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681281-88-9, 5-(2-BENZOTHIAZOLYL)-3-ETHYL-2-(-(METHYRelated Search:

Akt Inhibitor IV - CAS 681281-88-9 - Calbiochem

(E)-5-(benzo[d]thiazol-2-yl)-3-ethyl-2-(2-(methyl(phenyl)amino)vinyl)-1-phenyl-1H-benzo[d]imidazol-3-ium iodide

6-benzothiazol-2-yl-1-ethyl-2-[2-(methyl-phenyl-amino)-vinyl]-3-phenyl-3H-benzoimidazol-1-ium iodide

5-(Benzo[d]thiazol-2-yl)-3-ethyl-2-(2-(methyl(phenyl)amino)vinyl)-1-phenyl-1H-benzo[d]imidazol-3-ium iodide

6-(2-Benzothiazolyl)-1-ethyl-2-[2-(methylphenylamino)ethenyl]-3-phenyl-1H-benzimidazolium iodide

5-(2-BENZOTHIAZOLYL)-3-ETHYL-2-(-(METHY

681281-88-9

C31H27N4SI