4' 5'-BIS(N N-BIS(CARBOXYMETHYL)AMINO-
- Product Name
- 4' 5'-BIS(N N-BIS(CARBOXYMETHYL)AMINO-
- CAS No.
- 207124-64-9
- Chemical Name
- 4' 5'-BIS(N N-BIS(CARBOXYMETHYL)AMINO-
- Synonyms
- Calcein tetraethyl acid;Calceintetraethylacid, >97%;4' 5'-BIS(N N-BIS(CARBOXYMETHYL)AMINO-;Fluorescein-4',5'-bis(methyliminodiaceticacid);Calcein (free acid), green fluorescent Ca2+ indicator;Glycine, N,N'-[(3',6'-dihydroxy-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthene]-4',5'-diyl)bis(methylene)]bis[N-(carboxymethyl)-;2,2',2'',2'''-(((3',6'-Dihydroxy-3-oxo-3H-spiro[isobenzofuran-1,9'-xanthene]-4',5'-diyl)bis(methylene))bis(azanetriyl))tetraacetic acid;3H-IndoliuM, 2-[3-[1,3-dihydro-3,3-diMethyl-1-[6-oxo-6-(2-propyn-1-ylaMino)hexyl]-5-sulfo-2H-indol-2-ylidene]-1-propen-1-yl]-1-ethyl-3,3-diMethyl-5-sulfo-coMpd. with N,N-diethylethanaMine (1:2)
- CBNumber
- CB5503814
- Molecular Formula
- C30H26N2O13
- Formula Weight
- 622.53
- MOL File
- 207124-64-9.mol
4' 5'-BIS(N N-BIS(CARBOXYMETHYL)AMINO- Property
- solubility
- DMSO (Slightly, Heated), Methanol (Slightly, Heated, Sonicated)
- form
- Solid
- color
- Yellow to Dark Yellow
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
4' 5'-BIS(N N-BIS(CARBOXYMETHYL)AMINO- Chemical Properties,Usage,Production
Uses
Fluorescein Bis(methylene)]bis[N-(carboxymethyl)glycine] is an intermediate used in the synthesis of Calcein AM (C125400), which is a hydrophobic non-fluorescent probe that can permeate the plasma membrane and can be hydrolyzed to Calcein (sc-202090), which is an extremely fluorescent and negatively charged molecule. Calcein-AM can be used to stain living cells and in cytoplasmic Schwann cells has been observed to fluoresce bright green. Calcein-AM has been reported to be a neutral substrate for P-glycoprotein (Pgp) and multidrug resistance protein (MRP) and has been used in flow cytometry studies to analyze the function of P-gp and MRP.
4' 5'-BIS(N N-BIS(CARBOXYMETHYL)AMINO- Preparation Products And Raw materials
Raw materials
Preparation Products
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