Bobcat339 hydrochloride

Product Name: Bobcat339 hydrochloride
CAS No.: 2436747-44-1
Chemical Name: Bobcat339 hydrochloride
Synonyms: Bobcat339 hydrochloride;Bobcat339 hydrochloride ，S6682;1-([1,1'-Biphenyl]-3-yl)-4-amino-5-chloropyrimidin-2(1H)-one hydrochloride;1-([1,1'-Biphenyl]-3-yl)-4-amino-5-chloropyrimidin-2(1H)-one hydrochloride
CBNumber: CB55419688
Molecular Formula: C16H13Cl2N3O
Formula Weight: 334.2
MOL File: 2436747-44-1.mol

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Bobcat339 hydrochloride Property

form: Solid
color: Off-white to light yellow

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

ChemScene

Product number: CS-0087294
Product name: Bobcat339hydrochloride
Purity: 99.02%
Packaging: 5mg
Price: $250
Updated: 2021/12/16

ChemScene

Product number: CS-0087294
Product name: Bobcat339hydrochloride
Purity: 99.02%
Packaging: 10mg
Price: $350
Updated: 2021/12/16

ChemScene

Product number: CS-0087294
Product name: Bobcat339hydrochloride
Purity: 99.02%
Packaging: 50mg
Price: $950
Updated: 2021/12/16

ChemScene

Product number: CS-0087294
Product name: Bobcat339hydrochloride
Purity: 99.02%
Packaging: 100mg
Price: $1500
Updated: 2021/12/16

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Bobcat339 hydrochloride Chemical Properties,Usage,Production

Uses

Bobcat339 hydrochloride is a potent and selective cytosine-based inhibitor of TET enzyme, with the IC50s of 33 μM and 73 μM for TET1 and TET2, respectively. Bobcat339 hydrochloride is useful to the field of epigenetics and serves as a starting point for new therapeutics that target DNA methylation and gene transcription[1].

IC 50

TET1: 33 μM (IC₅₀); TET2: 73 μM (IC₅₀)

References

[1] Chua GNL, et al. Cytosine-Based TET Enzyme Inhibitors. ACS Med Chem Lett. 2019 Jan 31;10(2):180-185. DOI:10.1021/acsmedchemlett.8b00474
[2] Weirath NA, et al. Small Molecule Inhibitors of TET Dioxygenases: Bobcat339 Activity Is Mediated by Contaminating Copper(II). ACS Med Chem Lett. 2022 Apr 21;13(5):792-798. DOI:10.1021/acsmedchemlett.1c00677

Bobcat339 hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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Bobcat339 hydrochloride Suppliers

China 33 United States 4 Global 37

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2436747-44-1, Bobcat339 hydrochlorideRelated Search:

Bobcat339 hydrochloride

1-([1,1'-Biphenyl]-3-yl)-4-amino-5-chloropyrimidin-2(1H)-one hydrochloride

Bobcat339 hydrochloride ，S6682

2436747-44-1