ChemicalBook > CAS DataBase List > OSMI-4
OSMI-4
- Product Name
- OSMI-4
- CAS No.
- 2260791-14-6
- Chemical Name
- OSMI-4
- Synonyms
- OSMI-4;OSMI4,OSMI 4;OSMI-4 ,S8910;OSMI-4, 10 mM in DMSO;Ethyl (R)-N-(2-((7-chloro-2-oxo-1,2-dihydroquinoline)-6-sulfonamido)-2-(2-methoxyphenyl)acetyl)-N-(thiophen-2-ylmethyl)glycinate
- CBNumber
- CB55419800
- Molecular Formula
- C27H26ClN3O7S2
- Formula Weight
- 604.09
- MOL File
- 2260791-14-6.mol
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OSMI-4 Property
- Density
- 1.414±0.06 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- DMSO : 125 mg/mL (206.92 mM)
- form
- Solid
- pka
- 8.27±0.20(Predicted)
- color
- Light yellow to yellow
- InChIKey
- STPSLAZMEWZDAJ-JKXWNSIXNA-N
- SMILES
- [C@H](C1C=CC=CC=1OC)(NS(C1=C(C=C2NC(=O)C=CC2=C1)Cl)(=O)=O)C(=O)N(CC(=O)OCC)CC1SC=CC=1 |&1:0,r|
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OSMI-4 Chemical Properties,Usage,Production
Uses
OSMI-4 is a low nanomolar O-GlcNAc transferase (OGT) inhibitor, with an EC50 of 3 μM in cells.
References
[1] Martin SES, et al. Structure-Based Evolution of Low Nanomolar O-GlcNAc Transferase Inhibitors. J Am Chem Soc. 2018 Oct 24;140(42):13542-13545. DOI:10.1021/jacs.8b07328
OSMI-4 Preparation Products And Raw materials
Raw materials
Preparation Products
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