D-Phenylalanine, N-benzoyl-L-tryptophyl-, methyl ester

Product Name: D-Phenylalanine, N-benzoyl-L-tryptophyl-, methyl ester
CAS No.: 1435265-06-7
Chemical Name: D-Phenylalanine, N-benzoyl-L-tryptophyl-, methyl ester
Synonyms: HCH6-1;HCH6-1, 10 mM in DMSO;Methyl benzoyl-L-tryptophyl-D-phenylalaninate;Methyl N-benzoyl-L-tryptophyl-D-phenylalaninate;D-Phenylalanine, N-benzoyl-L-tryptophyl-, methyl ester;inhibit,inflammatory,FPR1,HCH6-1,cell infiltration,HCH6 1,antagonist,pulmonary,acute lung injury,lung diseases,ALI,Inhibitor,HCH61,HCH-6-1
CBNumber: CB55511388
Molecular Formula: C28H27N3O4
Formula Weight: 469.53
MOL File: 1435265-06-7.mol

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D-Phenylalanine, N-benzoyl-L-tryptophyl-, methyl ester Property

Boiling point:: 790.8±60.0 °C(Predicted)
Density: 1.259±0.06 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMSO: 250 mg/mL (532.45 mM)
form: Solid
pka: 13.25±0.46(Predicted)
color: White to off-white

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

DC Chemicals

Product number: 020433
Product name: HCH6-1
Packaging: 001
Price: $600
Updated: 2021/12/16

DC Chemicals

Product number: 020433
Product name: HCH6-1
Packaging: 006
Price: $1000
Updated: 2021/12/16

DC Chemicals

Product number: 020433
Product name: HCH6-1
Packaging: 007
Price: $2000
Updated: 2021/12/16

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D-Phenylalanine, N-benzoyl-L-tryptophyl-, methyl ester Chemical Properties,Usage,Production

Uses

HCH6-1 is a selective competitive antagonist of formyl peptide receptor 1 (FPR1) and has protective effects against acute lung injury (ALI).

in vivo

HCH6-1 (intraperitoneal injection; 50 mg/kg; 1 h before LPS spray or 30 min after LPS spray) alone does not induce airspace inflammation. HCH6-1 pretreatment reduces inflammatory cell infiltration and distortion of pulmonary architecture in the presence of LPS. HCH6-1 posttreatment shows inhibitory effects on neutrophil accumulation and lung damage in LPS-induced ALI mice^[1].

Animal Model:	C57BL/6 mice (20-25 g, 7-8 weeks old)^[1]
Dosage:	50 mg/kg
Administration:	Intraperitoneal injection; 50 mg/kg; 1 h before LPS spray or 30 min after LPS spray
Result:	Ameliorated ALI in LPS-induced mice.HCH6-1-mediated decreasing of neutrophil recruitment serves as a protective mechanism in ALI mice.

D-Phenylalanine, N-benzoyl-L-tryptophyl-, methyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

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D-Phenylalanine, N-benzoyl-L-tryptophyl-, methyl ester Suppliers

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1435265-06-7, D-Phenylalanine, N-benzoyl-L-tryptophyl-, methyl esterRelated Search:

5-DIMETHYLAMINO-1-NAPHTHALENESULFONIC ACID HYDRATE

D-Phenylalanine, N-benzoyl-L-tryptophyl-, methyl ester

HCH6-1

Methyl benzoyl-L-tryptophyl-D-phenylalaninate

inhibit,inflammatory,FPR1,HCH6-1,cell infiltration,HCH6 1,antagonist,pulmonary,acute lung injury,lung diseases,ALI,Inhibitor,HCH61,HCH-6-1

Methyl N-benzoyl-L-tryptophyl-D-phenylalaninate

HCH6-1, 10 mM in DMSO

1435265-06-7