ChemicalBook > CAS DataBase List > Pentixafor
Pentixafor
- Product Name
- Pentixafor
- CAS No.
- 1341207-62-2
- Chemical Name
- Pentixafor
- Synonyms
- CPCR4-2;Pentixafor;Pentixafor(CPCR4-2);1,4,7,10-Tetraazacyclododecane-1,4,7-triacetic acid, 10-[2-[[[4-[[[3-[(2R,5S,8S,14R)-5-[3-[(aminoiminomethyl)amino]propyl]-14-[(4-hydroxyphenyl)methyl]-1-methyl-8-(2-naphthalenylmethyl)-3,6,9,12,15-pentaoxo-1,4,7,10,13-pentaazacyclopentadec-2-yl]propyl]amino]carbonyl]phenyl]methyl]amino]-2-oxoethyl]...
- CBNumber
- CB56075915
- Molecular Formula
- C60H80N14O14
- Formula Weight
- 1221.36
- MOL File
- 1341207-62-2.mol
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Pentixafor Property
- form
- Solid
- color
- White to off-white
- InChIKey
- OSUJVKAXNLHVRB-HUMWUIFSSA-N
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N-Bromosuccinimide Price
TRC
- Product number
- P275603
- Product name
- Pentixafor
- Packaging
- 0.5mg
- Price
- $825
- Updated
- 2021/12/16
TRC
- Product number
- P275603
- Product name
- Pentixafor
- Packaging
- 1mg
- Price
- $1625
- Updated
- 2021/12/16
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Pentixafor Chemical Properties,Usage,Production
Uses
Pentixafor is a PET imaging agent used in the analysis of CXCR4 receptors in cancer.
in vivo
[68Ga]Pentixafor (15 MBq, intravenous injection, single dose) is suitable for PET imaging in the PC-3 prostate cancer xenograft model[2].
[18F]AlF-NOTA-Pentixather (0.30 MBq, intravenous injection, single dose) can target the CXCR4 receptor for specific PET imaging in the Daudi lymphoma xenograft SCID mouse model[4].
| Animal Model: | PC-3 prostate cancer xenograft (nude mouse) model[2] |
| Dosage: | 15 MBq (Pentixafor labeled with 68Gallium (68Ga), [68Ga]Pentixafor) |
| Administration: | Intravenous injection (i.v., injection via tail vein), single dose |
| Result: | Resulted in moderate contrast in PET imaging performed in the PC-3 tumor model. |
| Animal Model: | Daudi lymphoma xenograft (SCID mouse) model[4] |
| Dosage: | 0.30 MBq ([18F]AlF-NOTA-Pentixather, approx. 195 pmol/0.251 μg) |
| Administration: | Intravenous injection (i.v.), single dose, imaging performed at 60 minutes post-injection |
| Result: | Exhibited CXCR4-specific tumor accumulation, with low uptake in background organs. |
Pentixafor Preparation Products And Raw materials
Raw materials
Preparation Products
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Pentixafor Suppliers
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