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(±)-trans-GK563

Product Name
(±)-trans-GK563
CAS No.
2351820-19-2
Chemical Name
(±)-trans-GK563
Synonyms
(±)-trans-GK563;2-Oxetanone, 3-(4-phenylbutyl)-4-propyl-, (3R,4R)-rel-
CBNumber
CB56197338
Molecular Formula
C16H22O2
Formula Weight
246.34
MOL File
2351820-19-2.mol
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(±)-trans-GK563 Property

Boiling point:
364.2±11.0 °C(Predicted)
Density 
1.010±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
Chloroform: slightly soluble; DMSO: slightly soluble; Methanol: slightly soluble
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Biosynth Carbosynth
Product number
BG168610
Product name
GK 563
Packaging
10mg
Price
$145
Updated
2021/12/16
Biosynth Carbosynth
Product number
BG168610
Product name
GK 563
Packaging
50mg
Price
$435
Updated
2021/12/16
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(±)-trans-GK563 Chemical Properties,Usage,Production

Description

trans-(±)-GK563 is a potent β-lactone inhibitor of group VIA (GVIA) calcium-independent phospholipase A2 (GVIA iPLA2; IC50 = 1 nM).1 It is selective for GVIA iPLA2 over GVIA cPLA2 (IC50 = 22 μM). trans-(±)-GK563 (1 and 10 μM) inhibits apoptosis induced by IL-1β and IFN-γ in INS-1 β-cells.

References

1. Dedaki, C., Kokotou, M.G., Mouchlis, V.D., et al. β-Lactones: A novel class of Ca2+-independent phospholipase A2 (group VIA iPLA2) inhibitors with the ability to inhibit β-cell apoptosis J. Med. Chem. 62(6),2916-2927(2019).

(±)-trans-GK563 Preparation Products And Raw materials

Raw materials

Preparation Products

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(±)-trans-GK563 Suppliers

China 5 United States 1 Global 6
Shanghai Hongye Biotechnology Co. Ltd
Tel
400-9205774
Email
sales@glpbio.cn
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China
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6777
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ChemeGen(Shanghai) Biotechnology Co.,Ltd.
Tel
18818260767
Fax
QQ 3610331285
Email
sales@chemegen.com
Country
China
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11217
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Shanghai Yiyan Biotechnology Co. , Ltd.
Tel
021-69985186 13611928337
Email
3427709316@qq.com
Country
China
ProdList
7979
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58
Shanghai Yifei Biotechnology Co. , Ltd.
Tel
021-65675885 18964387627
Email
customer_service@efebio.com
Country
China
ProdList
11974
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58
TargetMol Chemicals Inc.
Tel
15002134094
Email
marketing@targetmol.cn
Country
China
ProdList
19711
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58

2351820-19-2, (±)-trans-GK563Related Search:


  • (±)-trans-GK563
  • 2-Oxetanone, 3-(4-phenylbutyl)-4-propyl-, (3R,4R)-rel-
  • 2351820-19-2