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AZITHROMYCIN-D3

Product Name
AZITHROMYCIN-D3
CAS No.
163921-65-1
Chemical Name
AZITHROMYCIN-D3
Synonyms
XZ-450-d3;Sumamed-d3;Ribotrex-d3;CP-62993-d3;Zitromax-d3;Zithromaz-d3;Trozocina-d3;Azitrocin-d3;AZITHROMYCIN-D3;D3-Azithromycin
CBNumber
CB5648148
Molecular Formula
C38H72N2O12
Formula Weight
748.98448
MOL File
163921-65-1.mol
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AZITHROMYCIN-D3 Property

Melting point:
125-1290C
storage temp. 
-20°C Freezer, Under Inert Atmosphere
solubility 
Chloroform (Slightly, Sonicated), Methanol (Slightly)
form 
Solid
color 
White to Off-White
EPA Substance Registry System
1-Oxa-6-azacyclopentadecan-15-one, 13-[(2,6-dideoxy-3-C-methyl-3-O-methyl-?-L-ribo-hexopyranosyl)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,8,10,12,14-hexamethyl-6-(methyl-d3)-11-[[3,4,6-trideoxy-3-(dimethylamino)-?-D-xylo-hexopyranosyl]oxy]-, (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)- (163921-65-1)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H317May cause an allergic skin reaction

H334May cause allergy or asthma symptoms or breathing difficulties if inhaled

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P272Contaminated work clothing should not be allowed out of the workplace.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P284Wear respiratory protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P333+P313IF SKIN irritation or rash occurs: Get medical advice/attention.

P342+P311IF experiencing respiratory symptoms: call a POISON CENTER or doctor/physician.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical
Product number
20675
Product name
Azithromycin-d3
Purity
≥99% deuterated forms (d1-d3)
Packaging
1mg
Price
$287
Updated
2024/03/01
TRC
Product number
A927002
Product name
Azithromycin-d3
Packaging
1mg
Price
$145
Updated
2021/12/16
Usbiological
Product number
A5050-01
Product name
Azithromycin-d3
Packaging
1mg
Price
$425
Updated
2021/12/16
Medical Isotopes, Inc.
Product number
D7047
Product name
Azithromycin-d3
Packaging
1mg
Price
$290
Updated
2021/12/16
AK Scientific
Product number
7398DU
Product name
Azithromycin-d3
Packaging
1mg
Price
$403
Updated
2021/12/16
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AZITHROMYCIN-D3 Chemical Properties,Usage,Production

Description

Azithromycin-d3 is intended for use as an internal standard for the quantification of azithromycin (Item No. 15004) by GC- or LC-MS. Azithromycin is a macrolide antibiotic. It is active against S. pneumoniae, S. aureus, N. gonorrhoeae, M. pneumoniae, H. pylori, C. trachomatis, and H. influenzae in vitro (MIC90s = <0.01-2 mg/L). Azithromycin increases survival in mouse models of intraperitoneal S. pyogenes, S. pneumoniae, E. faecalis, or H. influenzae infection (ED50s = 0.78, 8.7, 12.7, and 30.3 mg/kg, respectively). It inhibits replication of severe acute respiratory coronavirus 2 (SARS-CoV-2), but not Middle East respiratory syndrome CoV (MERS-CoV), when used at concentrations of 5 and 10 μM. Azithromycin also decreases plasma levels of IL-6, TNF-α, and IL-1β and increases survival in a mouse model of LPS-induced sepsis when administered at a dose of 100 mg/kg. Formulations containing azithromycin have been used in the treatment of a variety of bacterial infections.

Chemical Properties

White Solid

Uses

AzithroMycin-d3 can be used as Semi-synthetic macrolide antibiotic; related to Erythromycin A. Antibacterial.;AzithroMycin-d3 can be intended for use as an internal standard for the quantification of Azithromycin by GC- or LC-mass spectrometry.

IC 50

Macrolide

References

[1] M S KANATANI  B J G. The new macrolides. Azithromycin and clarithromycin.[J]. The Western journal of medicine, 1994, 160 1: 31-37.
[2] D GIRARD. Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.[J]. Journal of Antimicrobial Chemotherapy, 2005, 56 2: 365-371. DOI: 10.1093/jac/dki241
[3] AHMED MOSTAFA. FDA-Approved Drugs with Potent In Vitro Antiviral Activity against Severe Acute Respiratory Syndrome Coronavirus 2.[J]. ACS Applied Energy Materials, 2020. DOI: 10.3390/ph13120443
[4] ANASUYA PATEL. Azithromycin in Combination with Ceftriaxone Reduces Systemic Inflammation and Provides Survival Benefit in a Murine Model of Polymicrobial Sepsis.[J]. ACS Applied Energy Materials, 2018. DOI: 10.1128/aac.00752-18

AZITHROMYCIN-D3 Preparation Products And Raw materials

Raw materials

Preparation Products

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AZITHROMYCIN-D3 Suppliers

Canada 2 China 42 India 4 United States 4 Global 52
Artis Biotech Co. Ltd.
Tel
19138486554; 18108108965
Fax
0575-89298961
Email
sales@artisbio.com
Country
China
ProdList
2333
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J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
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76
Chemsky（shanghai）International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32321
Advantage
50
S.Z. PhyStandard Bio-Tech. Co., Ltd.
Tel
0755-83725681-603
Fax
+86 755 28094224
Country
China
ProdList
4496
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50
Shanghai TaoSu Biochemical Technology Co., Ltd.
Tel
021-33632979
Fax
021-34692979
Email
info@tsbiochem.com
Country
China
ProdList
8065
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58
Alta Scientific Co., Ltd.
Tel
022-6537-8550 15522853686
Fax
022-2532-9655
Email
sales@altasci.com.cn
Country
China
ProdList
4511
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Clearsynth Canada Inc.
Tel
+1.415.685.4395
Fax
+1.415.685.4395
Email
enquiry@clearsynth.com
Country
Canada
ProdList
912
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58
Shenzhen SUNGENING Bio-Medical Co., Ltd.
Tel
0755-28967200 13631290199
Fax
0755-28967200
Email
wxf@sungening.com
Country
China
ProdList
9629
Advantage
60
Shenzhen Polymeri Biochemical Technology Co., Ltd.
Tel
+86-400-002-6226 +86-13028896684;
Email
sales@rrkchem.com
Country
China
ProdList
57422
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58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
Tel
18818260767
Fax
QQ 3610331285
Email
sales@chemegen.com
Country
China
ProdList
11218
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58

163921-65-1, AZITHROMYCIN-D3Related Search:

METHANOL-D DIMETHYL SULFOXIDE-D6 Azithromycin Azithromycin Impurity 8 (4R,5S,6S)-4-Methoxy-4,6-dimethyltetrahydro-2H-pyran-2,5-diol Azithromycin Impurity 10 N-Desmethyl 13(4-C,4-O-methylene)-pyranosyl Azithromycin 4'-Hydroxy AzithroMycin Azithromycin Impurity 11 N-Desmethyl Azithromycin B AzithroMycin iMpurity Erythromycin B Oxime/(3R,4S,5S,6R,7R,9R,11S,12R,13R,14R,E)-6-(((2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-14-ethyl-7,12-dihydroxy-4-(((2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-10-(hydroxyimino)-3,5,7,9,11,13-hexamethyloxacyclotetradecan-2-one Argatroban Impurity 35 1-Oxa-6-azacyclopentadecan-15-one, 13-[(2,6-dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl)oxy]-2-ethyl-3,4,10,11-tetrahydroxy-3,5,6,8,10,12,14-heptamethyl-, (2R,3S,4R,5R,8R,10R,11R,12R,13S,14R)- beta-D-Desosamine Descladinose 6-N-Desmethyl Azithromycin Azithromycin dihydrate ACETONITRILE-D3

  • AZITHROMYCIN-D3
  • Azitrocin-d3
  • CP-62993-d3
  • Ribotrex-d3
  • Sumamed-d3
  • Trozocina-d3
  • XZ-450-d3
  • Zithromaz-d3
  • Zitromax-d3
  • [2H3]-Azithromycin
  • Azithromycin Impurity 41
  • Azithromycin D3Q: What is Azithromycin D3 Q: What is the CAS Number of Azithromycin D3 Q: What is the storage condition of Azithromycin D3 Q: What are the applications of Azithromycin D3
  • 3'-N-[[4-(Acetylamino)phenyl]sulfonyl]-3'-N-demethyl Azithromycin-d4
  • Caprylic Acid Impurity 65
  • D3-Azithromycin
  • 163921-65-1
  • C38H69D3N2O12
  • Intermediates & Fine Chemical
  • Isotope Labeled Compounds
  • Pharmaceuticals
  • Isotope Labelled Compounds
  • Isotope Labelled Compounds, Pharmaceuticals, Intermediates & Fine Chemical