ALPHA-HYDROXYFARNESYLPHOSPHONIC ACID

Product Name: ALPHA-HYDROXYFARNESYLPHOSPHONIC ACID
CAS No.: 148796-53-6
Chemical Name: ALPHA-HYDROXYFARNESYLPHOSPHONIC ACID
Synonyms: HFPA;HYDROXYFARNESYL PHOSPHATE;MONZTFSZTWQCKH-IJFRVEDASA-N;A-hydroxyfarnesylphosphonic acid;α-hydroxy Farnesyl Phosphonic Acid;alpha-Hydroxyfarnesylphosphonic aicd;ALPHA-HYDROXYFARNESYLPHOSPHONIC ACID;ALPHA-HYDROXYFARNESYL PHOSPHONIC ACID ETHANOL SOLUTION;αhydroxy Farnesyl Phosphonic Acid,α hydroxy Farnesyl Phosphonic Acid;(+/-)-1-HYDROXY-3,7,11-TRIMETHYL-2E,6E,10-DODECATRIENE-1-PHOSPHONIC ACID
CBNumber: CB5664393
Molecular Formula: C15H27O4P
Formula Weight: 302.35
MOL File: 148796-53-6.mol

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ALPHA-HYDROXYFARNESYLPHOSPHONIC ACID Property

storage temp.: −20°C
solubility: 10 mM Na2CO3: freely soluble; ETOH: >25 mg/ml; PBS pH 7.2: <25 μg/ml
form: A crystalline solid

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Safety

Hazard Codes: F,Xi
Risk Statements: 11-36/37/38
Safety Statements: 16-26-36-7
RIDADR: UN 1170 3/PG 2
WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 63420
Product name: α-hydroxy Farnesyl Phosphonic Acid
Purity: ≥98%
Packaging: 1mg
Price: $121
Updated: 2024/03/01

Cayman Chemical

Product number: 63420
Product name: α-hydroxy Farnesyl Phosphonic Acid
Purity: ≥98%
Packaging: 5mg
Price: $543
Updated: 2024/03/01

Cayman Chemical

Product number: 63420
Product name: α-hydroxy Farnesyl Phosphonic Acid
Purity: ≥98%
Packaging: 10mg
Price: $961
Updated: 2024/03/01

American Custom Chemicals Corporation

Product number: CHM0290283
Product name: ALPHA-HYDROXYFARNESYLPHOSPHONIC AICD
Purity: 96.00%
Packaging: 5MG
Price: $1452
Updated: 2021/12/16

AK Scientific

Product number: 1609AH
Product name: alpha-Hydroxyfarnesylphosphonicacid
Packaging: 5mg
Price: $702
Updated: 2021/12/16

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ALPHA-HYDROXYFARNESYLPHOSPHONIC ACID Chemical Properties,Usage,Production

Description

α-hydroxy Farnesyl phosphonic acid is a nonhydrolyzable analog of farnesyl pyrophosphate which acts as a competitive inhibitor of farnesyl transferase (FTase). At concentrations greater than 1 μM, α-hydroxy farnesyl phosphonic acid inhibits the processing of Ras in Ha-ras-transformed NIH3T3 cells.

Uses

α-hydroxy Farnesyl phosphonic acid is a nonhydrolyzable analog of farnesyl pyrophosphate which acts as a competitive inhibitor of farnesyl transferase (FTase). At concentrations greater than 1 μM, α-hydroxy farnesyl phosphonic acid inhibits the processing of Ras in Ha-ras-transformed NIH3T3 cells.

References

[1] Gibbs, et al. Selective inhibition of farnesyl-protein transferase blocks ras processing in vivo. J. Biol. Chem. 268(11), 7617-7620 (1993).

ALPHA-HYDROXYFARNESYLPHOSPHONIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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ALPHA-HYDROXYFARNESYLPHOSPHONIC ACID Suppliers

China 12 Switzerland 2 United Kingdom 2 United States 10 Global 26

BOC Sciences

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Shanghai Hongye Biotechnology Co. Ltd

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TargetMol Chemicals Inc.

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MedBioPharmaceutical Technology Inc

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Shanghai Yifei Biotechnology Co. , Ltd.

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TargetMol Chemicals Inc.

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Cayman Chemical Company

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Enzo Biochem Inc

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Santa Cruz Biotechnology Inc

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Aladdin Scientific

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148796-53-6, ALPHA-HYDROXYFARNESYLPHOSPHONIC ACIDRelated Search:

ALPHA-HYDROXYFARNESYLPHOSPHONIC ACID ALPHA-HYDROXYFARNESYLPHOSPHONIC ACID (E,E)-Farnesol

HYDROXYFARNESYL PHOSPHATE

HFPA

(+/-)-1-HYDROXY-3,7,11-TRIMETHYL-2E,6E,10-DODECATRIENE-1-PHOSPHONIC ACID

ALPHA-HYDROXYFARNESYLPHOSPHONIC ACID

A-hydroxyfarnesylphosphonic acid

alpha-Hydroxyfarnesylphosphonic aicd

ALPHA-HYDROXYFARNESYL PHOSPHONIC ACID ETHANOL SOLUTION

MONZTFSZTWQCKH-IJFRVEDASA-N

Phosphonic acid, P-[(2E,6E)-1-hydroxy-3,7,11-trimethyl-2,6,10-dodecatrien-1-yl]-

α-hydroxy Farnesyl Phosphonic Acid

αhydroxy Farnesyl Phosphonic Acid,α hydroxy Farnesyl Phosphonic Acid

148796-53-6

C15H27O4P

Cell Signaling and Neuroscience

Cell Biology

BioChemical

Post-translational Modification

G Protein Function

G Proteins and Cyclic Nucleotides