ChemicalBook > CAS DataBase List > Oxamic acid

Oxamic acid

Product Name
Oxamic acid
CAS No.
471-47-6
Chemical Name
Oxamic acid
Synonyms
Oxamate;2-aMino-2-oxoacetic acid;Oxalamic acid;Oxamic acid Oxalic acid monoamide;OXAMIC ACID;OXAMIDIC ACID;OxamicAcid>Oxamicacid,98%;Glycine, 2-oxo-;Oxamic acid 98%
CBNumber
CB5667743
Molecular Formula
C2H3NO3
Formula Weight
89.05
MOL File
471-47-6.mol
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Oxamic acid Property

Melting point:
207-210 °C (dec.) (lit.)
Boiling point:
165.08°C (rough estimate)
Density 
1.6193 (rough estimate)
refractive index 
1.4264 (estimate)
storage temp. 
2-8°C(protect from light)
solubility 
DMSO (Slightly), Methanol (Slightly), Water (Slightly)
form 
Crystalline Powder
pka
1.60±0.20(Predicted)
color 
White
Water Solubility 
Soluble in water 108 mg/mL.
Merck 
14,6917
BRN 
1743294
InChI
InChI=1S/C2H3NO3/c3-1(4)2(5)6/h(H2,3,4)(H,5,6)
InChIKey
SOWBFZRMHSNYGE-UHFFFAOYSA-N
SMILES
C(O)(=O)C(N)=O
CAS DataBase Reference
471-47-6(CAS DataBase Reference)
EPA Substance Registry System
Oxamic acid (471-47-6)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
TSCA 
Yes
HS Code 
29241990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
O3750
Product name
Oxamic acid
Purity
≥98%
Packaging
25g
Price
$229
Updated
2024/03/01
TCI Chemical
Product number
O0084
Product name
Oxamic Acid
Purity
>97.0%(T)(N)
Packaging
5g
Price
$31
Updated
2024/03/01
TCI Chemical
Product number
O0084
Product name
Oxamic Acid
Purity
>97.0%(T)(N)
Packaging
25g
Price
$91
Updated
2024/03/01
Alfa Aesar
Product number
B20344
Product name
Oxamic acid, 98%
Packaging
5g
Price
$29.65
Updated
2024/03/01
Alfa Aesar
Product number
B20344
Product name
Oxamic acid, 98%
Packaging
25g
Price
$91.65
Updated
2024/03/01
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Oxamic acid Chemical Properties,Usage,Production

Description

Oxamic acids also known to as oxalic acid monoamides have emerged as potent precursors for the generation of the carbamoyl radical. Oxamic acids can easily undergo decarboxylation through a single electron oxidation resulting in the generation of the reactive carbamoyl radical, which can then engage in diverse radical reactions or undergo a second single electron oxidation as originally unveiled by Minisci. Oxamic acids are thus versatile intermediates for the synthesis of nitrogen-containing organic molecules[1]. The oxidative decarboxylation of oxamic acids can be mediated through thermal, photochemical, electrochemical or photoelectrochemical means, generating carbamoyl radicals, which may further add to unsaturated systems to provide a broad range of important amides. Oxidative decarboxylation of oxamic acids also offers a straightforward entry for the preparation of urethanes, ureas, and thioureas.

Chemical Properties

Oxamic acid is a white, water-soluble solid. It is the monoamide ofoxalic acid. It can react with metal carbonates to form oxamate. Oxamic acid inhibits lactate dehydrogenase A.

Uses

Oxamic acid is an ozone oxidation product and is used in the synthesis of hydroxybenzimidazoles preparation as potential anti tumor agents targeting human lactate dehydrogenase A.This compound is suitable for lactate dehydrogenase (LDH) related research.

Application

Oxamic acid (OA) has applications in polymer chemistry. It increases the water solubility of certain polymers, including polyester,epoxide, and acrylic upon binding with them. Oxamic acid can be used as a reactant to prepare 6-phenanthridinecarboxamide by direct C-H carbamoylation reaction using ammonium persulfate in DMSO. It can also be used as an organic ligand to prepare functionalized metal oxide nanoparticles for various biological applications. OA along with p-aminobenzoic acid is used to functionalize Au nanoparticles for the development of a sensor to detect Fe3+ ions by the calorimetric method.

Definition

ChEBI: Oxamic acid is a dicarboxylic acid monoamide resulting from the formal condensation of one of the carboxy groups of oxalic acid with ammonia. It has a role as an Escherichia coli metabolite. It is a conjugate acid of an oxamate.

References

[1] Ikechukwu Martin Ogbu . “Oxamic acids: useful precursors of carbamoyl radicals.” Chemical Communications 58 55 (2022): Pages 7593-7607.

Oxamic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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Oxamic acid Suppliers

Shanghai Hengmao Biotechnology Co. , Ltd.
Tel
18817538189
Email
hmbsales@163.com
Country
China
ProdList
80
Advantage
58
Suzhouhongxiong
Tel
18051745768 18051745768
Email
Suzhouhongxiong@163.com
Country
China
ProdList
85
Advantage
58
Nanjing Habo Medical Technology Co., Ltd.
Tel
025-85760892 13376090521
Fax
025-85766769
Email
sales@habotech.com
Country
China
ProdList
978
Advantage
60
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Shanghai Longsheng chemical Co.,Ltd.
Tel
021-58099652-8005 13585536065
Fax
021-58099609
Email
bin.wu@shlschem.com
Country
China
ProdList
9809
Advantage
59
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42958
Advantage
64
Syntechem Co.,Ltd
Tel
Fax
E-Mail Inquiry
Email
info@syntechem.com
Country
China
ProdList
12984
Advantage
57
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View Lastest Price from Oxamic acid manufacturers

Sense Chemicals (Shanghai) Co., Ltd.
Product
Oxamic acid 471-47-6
Price
US $0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
ton
Release date
2023-03-02

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